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A 62-year-old woman from Bogotá, Colombia, had chronic diarrhea for 4 years. The diarrhea was lienteric, occurring day and night, with mucus but no blood. She had no significant weight loss, abdominal pain, or other systemic symptoms, and no notable medical history. Initial stool tests showed leukocytes and blood but no parasites. Routine lab tests were normal. Due to the chronic symptoms and nocturnal diarrhea, a colonoscopy was performed. It revealed numerous mobile, white worms in the right colon, identified as Trichuris trichiura, causing friable mucosa. She was diagnosed with trichuriasis, or human whipworm infection.
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http://dx.doi.org/10.17235/reed.2025.11074/2025 | DOI Listing |
United European Gastroenterol J
March 2025
Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption.
View Article and Find Full Text PDFJ Pharm Pract
March 2025
Department of Pharmacy Practice, Barry and Judy Silverman College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, USA.
Dicyclomine is an antimuscarinic agent approved for treatment of irritable bowel syndrome-associated abdominal pain. Intravenous (IV) administration should be avoided due to potential for thrombosis, but real-world evidence is generally lacking. This case report presents a thrombotic complication associated with inadvertent IV administration of dicyclomine.
View Article and Find Full Text PDFJ Clin Nurs
March 2025
School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.
Background: COVID-19 survivors may experience complex, distressing and persistent symptoms, referred to as long COVID, lasting months or years after diagnosis. More evidence is needed for effective long COVID screening and management.
Aim: To explore the clinical profile of long COVID and factors associated with its development.
BMC Cancer
March 2025
Department of Pediatrics, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, Liaoning, 110004, P.R. China.
Background: To analyze the correlation between vasoactive intestinal peptide (VIP) protein expression in neuroblastoma (NB) tumors and NB clinical features and prognosis.
Methods: Clinical data were collected from 91 patients with NB aged < 18 years who underwent tumor resection at the Shengjing Hospital of China Medical University between January 2015 and December 2021. VIP expression levels in tumor tissues were evaluated by immunohistochemistry, and the correlation between VIP expression intensity and NB clinical characteristics and prognosis was analyzed.
Animals (Basel)
February 2025
Nagaya Animal Medical Center, Nagoya 468-0024, Aichi, Japan.
Chronic enteropathy (CE) or chronic inflammatory enteropathy is a group of diseases with multiple and different etiologies characterized by chronic gastrointestinal signs such as vomiting, diarrhea, anorexia, weight loss for more than 3 weeks, and inflammatory cell infiltration, such as lymphoplasmacytic cells in the intestinal mucosal lamina propria. The diagnosis was histologically confirmed after excluding other diseases such as parasitic infections, tumors, pancreatitis, exocrine pancreatic insufficiency, metabolic diseases, and endocrine diseases, such as hypoadrenocorticism. Nutritional management depends on several important functions, such as digestion and absorption processes, digestive enzymes and nutritional transporters, and barrier functions.
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