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Methylprednisolone-Induced Liver Injury: Insights From FAERS Analysis and Comparison With DILIN Findings.
Liver Int
March 2025
Department of Science and Education, The Third Hospital of Quzhou, Quzhou, China.
Evaluation of liver injury in multiple sclerosis patients receiving pulsed steroid therapy.
Mult Scler Relat Disord
September 2022
Multiple Sclerosis Research Center, Neuroscience institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Neurology, Sina hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
Objectives: There is a paucity of literature about the methylprednisolone induced liver injury in multiple sclerosis (MS) patients. In this study, we intended to investigate the incidence, severity, and risk factors for liver injury in MS patients treated with pulsed methylprednisolone therapy.
Methods: This is a prospective observational study on MS patients treated with methylprednisolone pulses.
Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis.
Int J Mol Sci
June 2020
Department of Neurosurgery, CHA University School of medicine, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do 13496, Korea.
Tauroursodeoxycholic acid (TUDCA) is a US FDA-approved hydrophilic bile acid for the treatment of chronic cholestatic liver disease. In the present study, we investigate the effects of TUDCA on the proliferation and differentiation of osteoblasts and its therapeutic effect on a mice model of osteoporosis. Following treatment with different concentrations of TUDCA, cell viability, differentiation, and mineralization were measured.
View Article and Find Full Text PDFMethylprednisolone-Induced Hypersensitivity Reaction in a Liver Transplant Recipient.
Exp Clin Transplant
May 2022
From the Department of Pharmacy UNC Medical Center, Chapel Hill, North Carolina, USA.
Corticosteroids have an essential role as an immunosuppressive agent in transplant; because of their anti-inflammatory properties, they rarely cause an allergic reaction. Here, we report a liver transplant recipient who developed an allergic reaction to intravenous methylprednisolone sodium succinate. The deceased-donor orthotopic liver transplant recipient received intravenous methylprednisolone sodium succinate for induction during transplant, which was followed by another intravenous dose and oral prednisone taper.
View Article and Find Full Text PDFMethylprednisolone induced liver injury in a patient with multiple sclerosis.
J Gastrointestin Liver Dis
March 2020
Mayo Clinic, College of Medicine, Rochester, MN, USA.
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