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| http://dx.doi.org/10.1016/j.hrcr.2024.08.019 | DOI Listing |
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Successful catheter ablation for sustained ventricular tachycardia in right ventricular infarction after surgery for giant right coronary artery aneurysm: a case report.
Eur Heart J Case Rep
March 2025
Department of Cardiovascular Medicine, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Background: Post-infarction scar-related ventricular tachycardia (VT) originating from the right ventricular (RV) free wall in patients with RV infarction is rare.
Case Summary: A 75-year-old Asian male, with a history of RV infarction after surgery for a giant right coronary artery aneurysm, presented with sustained VT with left bundle branch block and inferior axis morphology. The activation mapping during the VT revealed a focal origin initially propagated from the anterior attachment of the RV wall, and mid-diastolic potentials (MDPs) were detected within the RV free wall close to the anterior attachment.
Acute Electrical Synchronization Achieved With Dynamic Atrioventricular Delays During Biventricular and Left Ventricular MultiPoint Pacing.
CJC Open
February 2025
Barts Heart Centre, St Bartholomew's Hospital, London, UK.
Background: Cardiac resynchronization therapy (CRT) response relies on 2 factors: when and where to pace. These factors may be enhanced by dynamic atrioventricular delays (AVDs) (eg, SyncAV CRT, Abbott Cardiovascular, Abbott Park, IL) and multisite left ventricular (LV) pacing (eg, MultiPoint Pacing [MPP], Abbott). Their individual and combined synchronization contributions have not been evaluated across a comprehensive spectrum of pacing configurations.
View Article and Find Full Text PDFThe STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells.
Cell Rep
March 2025
Institute for Myelin and Glia Exploration, Buffalo, NY, USA; Department of Biochemistry, Buffalo, NY, USA; Department of Neurology, State University of New York at Buffalo Jacob's School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
During peripheral nervous system development, Schwann cells undergo Rac1-dependent cytoskeletal reorganization as they insert cytoplasmic extensions into axon bundles to sort and myelinate individual axons. However, our understanding of the direct effectors targeted by Rac1 is limited. Here, we demonstrate that striatin-3 and MOB4 are Rac1 interactors.
View Article and Find Full Text PDFPhysiological Ventricular Pacing from the Right Side of the Septum by Engaging the Subendocardial Purkinje Network.
J Innov Card Rhythm Manag
February 2025
Department of Cardiology, Hammersmith Hospital Campus, National Heart & Lung Institute, Imperial College, London, UK.
Right ventricular (RV) pacing, particularly from the RV apex, causes bilateral ventricular dyssynchrony, reducing systolic and diastolic function, by delayed activation of the lateral left ventricle, resulting in a wide QRS with a left bundle branch block (LBBB) morphology. Alternative pacing strategies, such as His-bundle pacing and LBB area pacing, tend to be more physiological, avoiding this problem. The feasibility of attaining a narrow paced QRS from the RV septum has not been methodically examined.
View Article and Find Full Text PDFSafety and efficacy of prophylactic onlay resorbable synthetic mesh with a comprehensive wound bundle at laparotomy closure in high-risk emergency abdominal surgery: an observational study.
World J Emerg Surg
March 2025
Donegal Clinical Research Academy, Letterkenny University Hospital, Letterkenny, Donegal, Ireland.
Background: There has been a slow uptake of wound bundles and prophylactic mesh augmentation (PMA) strategies despite evidence supporting their role in reducing burst abdomens and incisional hernias (IH). This study evaluates outcomes of resorbable synthetic prophylactic mesh augmentation in reducing these rates and assesses the complication profile in emergency abdominal surgery.
Methods: A retrospective ethically approved observational study of all patients who underwent emergency open abdominal surgery using supplemental prophylactic onlay TIGR Mesh at Letterkenny University Hospital between September 2017 and April 2024 was undertaken to assess safety, complication profiles and outcomes.
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