Angioedema involves fluid accumulation into the interstitial spaces of the dermis, subcutaneous tissue, and mucosal surfaces. While usually benign and self-limited, angioedema can lead to laryngeal edema, a life-threatening condition. The most common causes are histamine-mediated allergic reactions. However, angioedema can also be mediated by bradykinin. Bradykinin-mediated angioedema can occur in the setting of hereditary deficiency of C1q esterase and after exposure to several medications. Drug-induced angioedema is most commonly a secondary complication of non-steroidal anti-inflammatory drug (NSAID) or sulfa drug use. All providers must be aware of the potential side effects of the medications they use or prescribe. We present a case of angioedema resulting from the use of technetium-99m sestamibi tracer injection during an adenosine nuclear stress test.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787052 | PMC |
| http://dx.doi.org/10.7759/cureus.76780 | DOI Listing |
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