Introduction: Pyogenic granulomas are benign, painless vascular tumors on the skin and mucosal surfaces. They are commonly found in the head and neck region, although their occurrence in the larynx is rare. The term "lobular capillary hemangioma" is now used to describe the histological appearance of these tumors more accurately. Predisposing factors for pyogenic granuloma of the larynx have been linked to prior traumatic injuries, such as intubation, previous surgeries, or laryngopharyngeal reflux.
Case Presentation: A 33-year-old male visited our clinic with complaints of progressive dysphonia and choking for two months. The patient did not experience dysphagia or dyspnea. There was no history of previous intubation, gastroesophageal reflux disease, or other chronic illnesses. Upon laryngoscopic examination, a polypoid lesion measuring 25×8 mm was found on the posterior commissure of the right vocal cord. No abnormalities were observed during the ear and nose examinations.
Discussion: Pyogenic granuloma, or lobular capillary hemangioma, is a hyperplastic lesion that develops on the skin and mucous membranes. It often occurs in response to trauma or hormonal factors. Histologically, pyogenic granulomas differ from granulation tissues due to their lobular arrangement of capillaries in the deeper portions of the lesion. The term "lobular capillary hemangioma" has been recently introduced to emphasize this phenomenon. Some of the conditions considered in the differential diagnosis include hemangioma, hemangioendothelioma, angiofibroma, angiosarcoma, Kaposi sarcoma, Wegener's granuloma, Crohn's disease, granulomatous infections such as tuberculosis and histoplasmosis, traumatic granuloma, carcinosarcoma, as well as verrucous and squamous cell carcinoma.
Conclusion: We present a case report of lobular capillary hemangioma of the larynx, including its histopathological diagnosis and management course.
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http://dx.doi.org/10.2147/IMCRJ.S494200 | DOI Listing |
Wien Med Wochenschr
March 2025
Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria.
Acquired digital fibrokeratoma (ADFK) is a rare benign mesenchymal tumor often presenting as a small, firm, hyperkeratotic lesion, typically located in the periungual or subungual regions of the digits. Though benign, ADFK can lead to significant functional or cosmetic issues and may be mistaken for more serious conditions such as squamous cell carcinoma or pyogenic granuloma. We report the case of a 36-year-old male with a 3- to 4‑year history of a progressively enlarging periungual tumor leading to nail deformity and mild pressure effects on the underlying bone.
View Article and Find Full Text PDFJ Ultrasound
March 2025
Department of Emergency Radiology, Santobono-Pausilipon Children Hospital, Naples, Italy.
Purpose: To demonstrate the utility of ultrasound and color Doppler examination in differentiating red skin lesions.
Methods: We used high-frequency probes to identify common features of infantile hemangioma that can help distinguish it from other red skin lesions.
Results: In the pediatric population red skin lesions are frequently encountered in clinical practice.
J Craniofac Surg
March 2025
Department of Surgery, Division of Plastic Surgery, Nemours Children's Hospital Wilmington, DE.
Introduction: Pediatric eyelid masses pose a diagnostic challenge, with overlapping presentations between infectious, inflammatory, and neoplastic etiologies. Subcutaneous pyogenic granulomas (SPG), a rare variant, can mimic malignant tumors such as soft tissue sarcomas, leading to potential delays in appropriate management. This case report details the surgical resection of a rapidly growing pediatric eyelid subcutaneous mass, ultimately diagnosed as a subcutaneous pyogenic granuloma with histologic variation.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India.
Osteosarcoma is a rare malignant tumor that primarily affects the jaw bones, with the low-grade chondroid variant being an uncommon subtype that often mimics benign lesions. This case report details the clinical presentation, histopathological findings, radiographic evidence, and treatment approach for a 23-year-old male who presented with recurrent gingival growth and pain in the lower anterior region. Initially misdiagnosed as a pyogenic granuloma, further evaluation revealed the presence of low-grade chondroid variant osteosarcoma.
View Article and Find Full Text PDFInt Med Case Rep J
March 2025
Department of Dermatology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, People's Republic of China.
Pyogenic granuloma (PG) is a benign vascular tumor that can be challenging to treat, particularly in aesthetically sensitive areas. We report a case of a 32-year-old man with a PG on the upper lip that did not respond to conventional treatments, including glucocorticoid injections and long-pulse 1064 nm laser therapy. Due to aesthetic concerns and the lack of response to these treatments, the patient was administered oral thalidomide at a nightly dose of 75 mg for 5 months, which resulted in complete regression without recurrence over a 3-year follow-up.
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