This case report on recurrent urinary tract infections (UTIs) caused by multidrug-resistant (MDR) in a post-renal transplant patient underscores the significant clinical challenge of managing MDR infections in immunocompromised individuals, particularly in the context of renal transplantation. The patient was treated with an extended infusion of meropenem, which offers prolonged drug exposure and enhances bactericidal activity against MDR pathogens. This approach is critical in overcoming the resistance mechanisms inherent to , thereby improving the likelihood of therapeutic success. The findings presented here highlight the potential efficacy of extended meropenem infusion in treating MDR infections, providing a valuable therapeutic option for clinicians facing similar cases. This report contributes to the growing evidence supporting advanced antibiotic administration techniques in managing complicated urinary tract infections in transplant in resource limited countries.
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http://dx.doi.org/10.3389/frtra.2024.1494016 | DOI Listing |
Pediatr Dermatol
March 2025
Department of Dermatology, Ankara Etlik City Hospital, Ankara, Turkey.
Anagen effluvium is a rare adverse effect of methotrexate therapy, generally associated with high-dose regimens. We report a 12-year-old girl who developed abrupt hair loss 1 week after inadvertently taking methotrexate 15 mg daily for five consecutive days (total 75 mg), without other signs of systemic toxicity. Trichoscopic examination and trichogram findings confirmed methotrexate-induced anagen effluvium, and spontaneous hair regrowth occurred after 2 months.
View Article and Find Full Text PDFPhys Ther
March 2025
Doctor of Physical Therapy Program, Nova Southeastern University, Tampa Bay Regional Campus, Clearwater, FL 33759, United States.
Objective: The prevalence of students with disabilities in physical therapist education programs in the United States is <1%. This case report explored the experiences surrounding a specific, unique individual student with blindness or visual impairment (BVI) within the context of an entry-level physical therapist program. The purpose was not merely to describe 1 student's journey but to capture the complex dynamics and shifts in perceptions of students, faculty, staff, and clinicians.
View Article and Find Full Text PDFPalliat Support Care
March 2025
Departments of Psycho-oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Objectives: Naldemedine is a peripherally acting μ-opioid receptor antagonist used to treat opioid-induced constipation. As this drug does not cross the blood-brain barrier, it is believed that patients without brain metastases do not experience opioid withdrawal symptoms.
Methods: Here, we experienced a case in which a cancer patient without brain metastasis presented with anxiety and restlessness that was severe enough to interfere with daily life.
J Surg Case Rep
March 2025
Plastic Surgery Department, St James's Hospital, Dublin, D08 NHY1, Ireland.
High pressure injection injuries to upper extremities are largely rare occurrences. The direct and indirect effects of the injected substance can cause debilitating consequences for those affected and can lead to digit amputation. This case series includes three patients with high pressure injection injuries admitted to a single tertiary centre over one year.
View Article and Find Full Text PDFJ Surg Case Rep
March 2025
Urology Department, Mercy University Hospital, Grenville Place, Cork City T12 WE28, Ireland.
Retrocaval ureter (RU) is a rare congenital malformation where the ureteric pathway is altered, passing posteriorly around the inferior vena cava (IVC). Occasionally, this leads to the IVC compressing the ureter, resulting in obstruction. In this report, we discuss a male who presented with severe right-sided flank pain and was otherwise well with no significant medical, urological, or birth history.
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