Objective: To compare the embolization outcomes and complications of the LEO Baby and Neuroform Atlas stents in the endovascular treatment of intracranial wide-neck aneurysms.
Methods: We identified patients with intracranial aneurysms treated with LEO Baby (n = 163) or Atlas (n = 65) stent-assisted coiling between October 2018 and February 2023. A retrospective analysis of demographics, aneurysm characteristics, embolization outcomes, and procedure-related complications was performed. Propensity score matching analysis with a ratio of 1:2 was used to balance the patient selection bias that existed between the 2 cohorts.
Results: Compared to the Atlas cohort, the LEO Baby cohort had a higher rate of immediate successful embolization (95.6% vs. 78.5%, P < 0.001) and a lower rate of incomplete embolization at midterm follow-up (4.0% vs. 18.6%, P = 0.006), but there was no significant difference for either after matching for a 1:2 propensity score (P = 0.091 and P = 0.081, respectively). Procedure-related complications were 10.4% (17/163) in the LEO Baby cohort and 7.7% (5/65) in the Atlas cohort. At midterm angiographic follow-up, recanalization occurred in 0.8% (1/124) of the LEO Baby cohort and 4.7% (2/43) of the Atlas cohort. Complication and recanalization rates for both stents were not statistically different before (P = 0.701 and P = 0.332, respectively) and after (P > 0.999 and P > 0.999, respectively) propensity score matching.
Conclusions: Both LEO Baby and Atlas are safe and effective in the treatment of intracranial aneurysms, and they are similar in terms of aneurysm embolization outcomes and complication rates.
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http://dx.doi.org/10.1016/j.wneu.2025.123747 | DOI Listing |
Clin Radiol
February 2025
Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, China. Electronic address:
Aim: Distal anterior cerebral artery (ACA) aneurysms are a rare and difficult entity to manage. In this single-centre retrospective case series, we aimed to investigate the safety and efficacy of LEO Baby stent-assisted coiling (SAC) for the treatment of unruptured distal ACA aneurysms.
Material And Methods: This retrospective study aims to identify patients with unruptured distal ACA aneurysms treated with LEO Baby stent-assisted coiling in a single institution from October 2018 to October 2022.
Am J Case Rep
February 2025
Department of Radiology, Hopital Parini, AUSL Valleè d'Aoste, Aosta, Italy.
BACKGROUND Surgery was once considered the only possible treatment for uterine fibroids. However, a more conservative treatment approach can preserve women's reproductive capacity. In recent years, uterine artery embolization (UAE) and medical treatments have been introduced as a minimally or non-invasive therapeutic option.
View Article and Find Full Text PDFJ Allergy Clin Immunol
March 2025
Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia; Centre for Food Allergy Research, Murdoch Children's Research Institute, Parkville, Australia; Allergy Immunology, Murdoch Children Research Institute, Parkville, Australia. Electronic address:
Background: Skin lipids are crucial components of the skin barrier. Individuals with atopic dermatitis (AD or eczema) have a different skin lipid profile from those without. However, whether altered skin lipids precede and predict the subsequent risk of AD remained unclear, especially for different AD phenotypes.
View Article and Find Full Text PDFAllergy Asthma Clin Immunol
February 2025
Division of Clinical Immunology & Allergy, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)-mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the goal of desensitizing an individual to the food allergen. Current Canadian clinical practice guidelines for OIT recommend this form of therapy as an option in patients with food allergy. The intervention should be prioritized in the infant and toddler population, in which it is particularly well tolerated and can lead to sustained unresponsiveness (also sometimes referred to as remission).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!