The influence of breech and vertex delivery on intrapartum fetal and neonatal mortality was studied in 8,863 infants delivered at Kurashiki Central Hospital Perinatal Center. The rate of mortality was studied in cases without fatal congenital anomalies. The frequency of congenital anomaly was also studied in 8,863 infants delivered by breech and vertex presentation. Infants were divided into five groups according to their birth weight: 99g or less, 1,000-1,499g, 1,500-1,999g, 2,000-2,499g and 2,500g or more. Infants were also grouped into four by gestational age: 24-27 weeks, 28-31 weeks, 32-36 weeks and 37 weeks or more. The total infant mortality rate was 4.9% in breech delivery, and 0.5% in vertex delivery, respectively. This difference was statistically significant. The rate of major congenital anomaly in breech delivery was significantly higher than in vertex delivery. The rate of premature deliveries in breech presentation was also significantly higher than in vertex delivery. The rate of mortality in the group weighing 1,000-1,499g was 50.0% in breech delivery, and 17.6% in vertex delivery, respectively. This difference was statistically significant. The rate of mortality in the group delivered at 28-31 weeks gestational age was 62.5% in breech delivery, and 15.4% in vertex delivery, respectively (statistically significant). The rate of severe neonatal asphyxia in infants delivered at 28-31 weeks of gestational age was significantly higher in breech delivery than in vertex delivery.
Download full-text PDF |
Source |
---|
Discov Nano
January 2025
Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, Shaanxi, China.
Human lens epithelial cells (hLECs) are critical for lens transparency, and their aberrant metabolic activity and gene expression can lead to cataract. Intracellular delivery to hLECs, especially to sub-cellular organelles (e.g.
View Article and Find Full Text PDFMinerva Obstet Gynecol
January 2025
Obstetrics and Gynecology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Background: Vaginal delivery in twins is feasible but challenging. Successful vaginal delivery of a non-vertex second twin depends on knowledge of specific obstetrical maneuvers. Skill acquisition at the patient's bedside is difficult, making simulation training an integral part of obstetrics and gynecology residency programs.
View Article and Find Full Text PDFJ Cyst Fibros
January 2025
Leeds Institute of Medical Research, University of Leeds, School of Medicine, Leeds, United Kingdom; The Leeds Adult CF Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom. Electronic address:
Background: Whether improvements in gastrointestinal (GI) symptoms observed with Elexacaftor/Tezacaftor/Ivacaftor (ETI) treatment are sustained in the longer-term requires exploration. This study investigated how GI-symptoms change with longer-term ETI use in pancreatic insufficient adults with cystic fibrosis (awCF).
Methods: Participants completed up to three abdominal symptom questionnaires, employing the validated CFAbd-Score.
Proc Natl Acad Sci U S A
January 2025
Innovative Genomics Institute, University of California, Berkeley, CA 94720.
The widespread application of genome editing to treat and cure disease requires the delivery of genome editors into the nucleus of target cells. Enveloped delivery vehicles (EDVs) are engineered virally derived particles capable of packaging and delivering CRISPR-Cas9 ribonucleoproteins (RNPs). However, the presence of lentiviral genome encapsulation and replication proteins in EDVs has obscured the underlying delivery mechanism and precluded particle optimization.
View Article and Find Full Text PDFJ Racial Ethn Health Disparities
January 2025
Department of Obstetrics & Gynecology, Kaiser San Francisco, San Francisco, CA, USA.
Objective: To evaluate race and ethnicity differences in rates of cesarean delivery on maternal request (CDMR) in nulliparous, term, singleton, vertex presentation (NTSV) cesarean deliveries.
Methods: We conducted a retrospective cohort study of NTSV cesarean deliveries within our institution from 2016 to 2020. The primary outcome was CDMR and the primary predictor was maternal race and ethnicity.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!