Leprosy is one of the major mycobacterial diseases caused by Mycobacterium (M.) leprae or M. lepromatosis. Although there is scientific evidence for human leprosy from the Iron Age, it became more prevalent during medieval times, deeply affecting society and social life. Leprosy was considered a consequence of sin and was later thought to a certain extent to be inherited. Lepers were declared legally dead and excluded from normal social life. In the 14th century, the medicalization of leprosy began. Leprosaria became the earliest hospitals in the Middle Ages that were specialized for a single disease. They had their own churches, cemeteries, and priests. Treatment included medical and spiritual approaches.
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http://dx.doi.org/10.1016/j.clindermatol.2025.01.005 | DOI Listing |
Acta Anaesthesiol Scand
April 2025
Department of Anesthesiology and Intensive Care Medicine, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg and Section for Cardiothoracic Anesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden.
Background: Acute kidney injury (AKI) is a serious complication after lung transplantation, but the reported incidence varies in the literature. No data on AKI have been published from the Swedish lung transplantation program.
Methods: The aim of our study was to investigate the incidence, perioperative risk factors, and effects of early postoperative acute kidney injury (Kidney Disease Improving Global Outcomes [KDIGO] criteria) after lung transplantation.
Thorac Cancer
March 2025
Department of Thoracic Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Background: Few malignancies provoke as many controversies about treatment as pleural mesothelioma. There is limited experience with novel radiotherapy techniques worldwide in adjuvant and particularly in neoadjuvant settings within multimodality treatment. The objective of the current study was to investigate the long-term outcome of neoadjuvant and adjuvant pleural intensity-modulated radiotherapy (IMRT) combined with macroscopic complete resection with or without chemotherapy.
View Article and Find Full Text PDFEpidemiol Prev
March 2025
Center for Nursing Research and Innovation (CeNRI), Università Vita-Salute San Raffaele, Milano.
Background: urge urinary incontinence (UUI) is the involuntary loss of urine accompanied or immediately preceded by a sudden and strong desire to urinate that cannot be delayed or that is difficult to postpone. Data claim that UUI increases significantly from 40 to 65 years, which is why this specific age group, which has been little studied in the literature, deserves to be investigated. Moreover, they are socially active and working women who represent a social and economic resource for the country: therefore, their malaise is not only a personal problem, but also a problem for the society.
View Article and Find Full Text PDFThorac Cancer
March 2025
Department of Respiratory Medicine and Hematology, Hyogo Medical University, Nishinomiya, Japan.
Background: Bone metastasis (BoM) is common in advanced cancer, but its incidence in pleural mesothelioma (PM) remains unclear. This study aimed to determine the incidence of BoM in PM patients and assess its prognosis and risk factors to clarify its clinical significance.
Methods: A retrospective analysis was conducted on 515 histologically confirmed PM patients enrolled between January 2011 and December 2020.
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