Effects of exercise interventions on cognition, physical function and quality of life among older adults with cognitive frailty: A systematic review and meta-analysis.

Geriatr Nurs

School of Nursing, Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province, China; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Wuhan, Hubei Province, China; Hubei Shizhen Laboratory, Wuhan, Hubei Province, China. Electronic address:

Published: January 2025

Objectives: To explore the effects of exercise interventions on cognition, physical function, and quality of life among older adults with cognitive frailty.

Methods: A systematic review and meta-analysis were conducted (PROSPERO [CRD42024532608]). PubMed, Web of Science, Cochrane Library, Embase, CNKI, WanFang, VIP, and SinoMed databases were searched from inception until December 18, 2023.

Results: We found exercise improved overall cognition, physical frailty, walking ability, gait speed, and so on among older adults with cognitive frailty, but the effect on physical fitness and quality of life was insignificant. Subgroup analysis revealed exercise conducted ≥3 times per week, each session lasting ≤45 min and cycle≤12 weeks, had better-improved cognition. Traditional mind-body exercises like Baduanjin were more effective than resistance training for enhancing cognition.

Conclusions: Exercise intervention benefits overall cognition and most physical functions, but its impact on physical fitness and quality of life remains to be confirmed by future studies.

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http://dx.doi.org/10.1016/j.gerinurse.2025.01.006DOI Listing

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