Recognizing the broader accessibility of iodized salt compared to wheat flour, the Ethiopian government is considering fortification of iodized salt with folic acid, and possibly vitamin B, to address the high incidence of neural tube defects (NTDs) in Ethiopia. To prepare for this program, we assessed practices related to edible salt procurement and consumption, and the acceptability of novel salts fortified with iodine and folic acid (double-fortified salt, DFS) or iodine, folic acid, and vitamin B (triple-fortified salt, TFS) compared to iodized salt (IS). We surveyed 840 women of reproductive age in urban (Addis Ababa) and rural (Gimbichu Woreda) areas to describe their salt preferences and practices and used a three-point hedonic scale to evaluate the sensory acceptability of fine and coarse forms of DFS, TFS, and IS for color, taste, aroma, texture and overall acceptability. We found that women were the primary salt purchasers (72.8% rural, 97.4% urban) for household. Rural women preferred coarse salt (76.1%), whereas urban women preferred fine salt (42.4%) or both types (30.0%). All salts received favorable mean sensory ratings (≥ 2.1), with fine salt preferred for all sensory characteristics ( < 0.05). Fine IS (2.8 ± 0.5) was rated slightly higher than DFS (2.6 ± 0.8) and TFS (2.5 ± 0.8) ( < 0.05). Rural women were more willing to purchase DFS (79.2%) and TFS (73.0%) than urban women (65.0% DFS, 63.8% TFS). In conclusion, DFS and TFS are highly acceptable in Ethiopia, with women being the key target for their introduction. Mandatory fortification of both coarse and fine salts is recommended to maximize reach.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780718PMC
http://dx.doi.org/10.1002/fsn3.70012DOI Listing

Publication Analysis

Top Keywords

folic acid
20
iodine folic
16
salt
13
acid vitamin
12
iodized salt
12
fortified salt
8
salt iodine
8
women reproductive
8
reproductive age
8
women preferred
8

Similar Publications

Recognizing the broader accessibility of iodized salt compared to wheat flour, the Ethiopian government is considering fortification of iodized salt with folic acid, and possibly vitamin B, to address the high incidence of neural tube defects (NTDs) in Ethiopia. To prepare for this program, we assessed practices related to edible salt procurement and consumption, and the acceptability of novel salts fortified with iodine and folic acid (double-fortified salt, DFS) or iodine, folic acid, and vitamin B (triple-fortified salt, TFS) compared to iodized salt (IS). We surveyed 840 women of reproductive age in urban (Addis Ababa) and rural (Gimbichu Woreda) areas to describe their salt preferences and practices and used a three-point hedonic scale to evaluate the sensory acceptability of fine and coarse forms of DFS, TFS, and IS for color, taste, aroma, texture and overall acceptability.

View Article and Find Full Text PDF

Thermodynamic therapy (TDT) is a promising alternative to photodynamic therapy (PDT) by absorbing heat through thermosensitive agents (TSAs) to generate oxygen-irrelevant highly toxic free radicals. Therefore, TDT can be a perfect partner for photothermal therapy (PTT) to achieve efficient synergistic treatment of anoxic tumors using a single laser, greatly simplifying the treatment process and overcoming hypoxia limitations. However, the issues of how to improve the stability and delivery efficiency of TSAs still need to be addressed urgently.

View Article and Find Full Text PDF

Plumbagin ameliorates renal fibrosis by suppressing epithelial-mesenchymal transition.

Biochem Biophys Res Commun

January 2025

Department of Biomedical Laboratory Science, Yonsei University MIRAE Campus, Wonju, 26493, South Korea. Electronic address:

Renal fibrosis is a common pathological feature of chronic kidney diseases (CKDs), driven by excessive extracellular matrix (ECM) accumulation. Despite its prevalence, therapeutic candidates specifically targeting fibrosis are limited, and the role of renal tubular epithelial cells in fibrosis pathogenesis remains unclear. In this study, we evaluated the anti-fibrotic effects of Plumbagin, a plant-derived natural compound, using a folic acid-induced renal fibrosis model that simulates proximal tubular injury-driven fibrosis.

View Article and Find Full Text PDF

Purpose: Pancreatic cancer is one of the deadliest cancers in the world. In Armenia, it is 12th by incidence. The aim of this study is to evaluate treatment and outcomes of pancreatic cancer in Armenia during the past 12 years.

View Article and Find Full Text PDF

Superparamagnetic iron oxide nanoparticles (SPIONs) are known to be good MRI contrasts, but they have a high tendency to aggregate and their biocompatibility is limited. Hyaluronic acid is highly biocompatible, can provide SPION with colloidal stability, and interacts specifically with tumor cells through the CD44 receptor; therefore, it was used as a stabilizing layer. We successfully obtained SPION coated with hyaluronic acid and further functionalized it with folic acid to construct a dual-targeted system.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!