This case report describes rare accurate historical documentation of progressive reduction in effort tolerance over time in a patient with untreated congenital heart disease and pulmonary hypertension.
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http://dx.doi.org/10.1016/j.jaccas.2024.102802 | DOI Listing |
JACC Case Rep
January 2025
Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
This case report describes rare accurate historical documentation of progressive reduction in effort tolerance over time in a patient with untreated congenital heart disease and pulmonary hypertension.
View Article and Find Full Text PDFOncogenesis
January 2025
Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Diffuse large B-cell lymphoma (DLBCL) is characterized by its aggressive nature and resistance to standard chemotherapy, necessitating the development of new therapeutic approaches. The emergence of natural products and their derivatives has notably influenced cancer treatment, making morusinol, a medicine-derived monomer, a promising candidate. Here, we showed that morusinol exerted antitumor effects on DLBCL in vitro by inducing apoptosis and cell cycle arrest.
View Article and Find Full Text PDFVaccine
January 2025
Medical Technology Innovation Center, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. Electronic address:
This study was conducted at 112 government and Juntendo University hospitals in February 2021 for the primary series of SARS-CoV-2 vaccinations. We compared the timing of solicited adverse event (AE) onset and prevalence of unsolicited AEs for Pfizer, Moderna, and AstraZeneca vaccines in a nationwide, large-scale prospective cohort study. The Pfizer and Moderna mRNA vaccines were associated with a higher frequency of fever after the second dose than after the first dose.
View Article and Find Full Text PDFMar Biotechnol (NY)
January 2025
Marine Ecology Research Center, Ministry of Natural Resources, First Institute of Oceanography, Qingdao, 266061, China.
Planiliza haematocheilus, a teleostan species noted for its ecological adaptability and economic significance, thrives in both freshwater and marine environments. This study presents a novel chromosome-level genome assembly through Hi-C, PacBio CCS, and Illumina sequencing methods. The assembled genome has a final size of 651.
View Article and Find Full Text PDFFront Physiol
January 2025
Department of Health Sciences, Environmental Physiology Group, Mid Sweden University, Östersund, Sweden.
Breath-hold diving performances are typically better in men than in women. However, it is still being determined if there are differences in the physiological responses to breath-holding between the sexes. We conducted a study comparing the maximum breath-hold duration, heart rate (HR) reduction, peripheral oxygen saturation (SpO), and spleen volume and contraction in 37 men and 44 women, all of whom had no prior breath-holding experience.
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