Background: Caffeine is a well-established ergogenic aid that enhances physical performance and recovery. However, its dose-dependent effects on key performance metrics in combat sports like kickboxing remain insufficiently explored.
Objective: This study aimed to evaluate the effects of varied doses of acute caffeine supplementation on performance indices and perceived muscle pain in kickboxing athletes.
Methods: Twelve kickboxing athletes participated in 3 exercise sessions with either caffeine supplementation (3 mg/kg [C3], 6 mg/kg [C6]) or placebo (PLA). A 1-wk washout period occurred between exercise trials. Caffeine was supplemented 60 min before each exercise session. In each session, participants first performed a vertical jump and the Wingate anaerobic tests. After a 45-min rest, they completed the Bruce maximal aerobic treadmill test. Measured performance variables included vertical jump height, Wingate test outcomes (relative power [peak, mean power, and lowest], and fatigue index), maximal oxygen consumption (VO₂max), oxygen consumption at the ventilatory threshold (VT), time-to-exhaustion, rating of perceived exertion (RPE), and muscle soreness assessed immediately, at 2 h, and 12 h postexercise.
Results: C3 and C6 significantly increased time-to-exhaustion following treadmill testing ( < 0.05) but had no effect on the Wingate fatigue index ( > 0.05). Compared with PLA, C3 and C6 significantly increased vertical jump ( < 0.05). C3 significantly increased relative peak power ( < 0.05), whereas C6 and PLA did not during the Wingate test ( > 0.05). Muscle soreness after 2 h showed a significant decrease after C6 compared with C3 and PLA ( < 0.05). In contrast, no significant effect was observed for VO, %VO at VT, and RPE ( > 0.05) for all treatments.
Conclusions: Acute supplementation of 3 to 6 mg/kg doses of caffeine-induced relative improvements in anaerobic and lower-body muscular power, muscle soreness, and time-to-exhaustion in male kickboxing athletes.
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http://dx.doi.org/10.1016/j.cdnut.2024.104538 | DOI Listing |
Curr Drug Saf
January 2025
National Center Chalbi Belkahia of Pharmacovigilance, Department of Collection and Analysis of Adverse Effects, Tunis, Tunisia, University of Tunis El Manar, Faculty of Medicine, Research unit: UR17ES12, Tunis, Tunisia.
Background: Trimethoprim-Sulfamethoxazole (TMP-SMX) is a commonly used antibiotic for the treatment of several infections, such as urinary tract infections, respiratory infections, and in certain cases, septic arthritis. Rhabdomyolysis (RM) is very rare and less than 20 cases have been reported, so far, in the literature, in particular in immunocompromised patients. Here, we report a case of TMP-SMX-induced RM in an immunocompetent patient, adding to the limited data on this association.
View Article and Find Full Text PDFCurr Dev Nutr
January 2025
Department of Exercise Physiology, University of Isfahan, Isfahan, Iran.
Background: Caffeine is a well-established ergogenic aid that enhances physical performance and recovery. However, its dose-dependent effects on key performance metrics in combat sports like kickboxing remain insufficiently explored.
Objective: This study aimed to evaluate the effects of varied doses of acute caffeine supplementation on performance indices and perceived muscle pain in kickboxing athletes.
PLoS Negl Trop Dis
January 2025
Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Background: During the 2023-dengue outbreak in Bangladesh, a diagnostic evaluation study was conducted to investigate concurrent Zika virus (ZIKV) and dengue virus (DENV) transmission in Dhaka in 2023.
Aims: The study explored to simultaneously detect the presence of ZIKV, DENV, and/or CHIKV while considering relevant clinical and epidemiological risk factors, using a real-time multiplex RT-PCR system. Following this, it was planned to sequence the selected samples to identify genetic variations of the ZIKV infections within the population.
Front Oncol
January 2025
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Objective: The prevalence of long COVID among cancer patients remains unknown. This study aimed to determine the prevalence of long COVID and explore potential risk factors among cancer patients.
Methods: A systematic search was performed on PubMed, Web of Science, and Embase from database inception until 21 March 2024, to identify studies that reported long COVID in cancer patients.
Radiol Case Rep
March 2025
Departement of radiology HER, University Mohammed V Rabat, Rabat, Morocco.
We report the case of a 15-year-old girl who presented with a 2-month history of severe fatigue and rapidly worsening myalgia. Biological tests revealed hypereosinophilia and an inflammatory syndrome. MRI showed increased signal intensity in the superficial and deep aponeurotic layers on T2-weighted images, with moderate fascia enhancement after contrast administration.
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