In patients with severe refractory immune thrombocytopenia (ITP), especially those unable to receive blood transfusions due to religious beliefs, alternative non-cytotoxic therapies are important to avoid worsening cytopenias. Immunomodulatory agents such as mycophenolate mofetil and daratumumab should be used alongside traditional therapies including steroids, IVIG and rituximab.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780247PMC
http://dx.doi.org/10.1002/ccr3.70102DOI Listing

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