Brucellosis is a significant global challenge, but there has been a lack of epidemiological studies on brucellosis in Xinjiang from a change point perspective. This study aims to bridge this gap by employing sequence decomposition and identifying significant change points, with datasets sourced from the Xinjiang Disease Prevention and Control Information System. This study employed the BEAST algorithm to decompose the brucellosis time series in Xinjiang from 2010 to 2023, while simultaneously identifying change points in the decomposed seasonal and trend components. The probability of four change points occurring within the seasonal component is 0.8950. And the locations where these four change points occur and the probabilities associated with each change point are August 2013 ([Formula: see text]), August 2017 ([Formula: see text]), February 2022 ([Formula: see text]), and May 2023 ([Formula: see text]), respectively. The probability of the existence of five change points in the trend factors of brucellosis in Xinjiang is highest ([Formula: see text]). The times at which these five change points occur, along with the probabilities of change at those moments, are as follows: March 2013 ([Formula: see text]), August 2015 ([Formula: see text]), July 2017 ([Formula: see text]), February 2020 ([Formula: see text]), and May 2023 ([Formula: see text]). Change point analysis holds significant utility within the field of epidemiology. These discoveries furnish pivotal insights for epidemiological investigations and the development of early warning systems tailored to brucellosis.

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http://dx.doi.org/10.1038/s41598-025-88508-0DOI Listing

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