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The US withdrawal from the Paris Climate Agreement: could it trump progress on climate change and health?
BMJ
January 2025
Ethnicity and Health Unit, Department of Primary Care and Public Health, Imperial College London, UK.
Association Between GABRG2 and Self-Rating of the Effects of Alcohol in a French Young Adult Sample.
Risk Manag Healthc Policy
January 2025
Université Paris Cité, Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Team Vulnerability of Psychiatric and Addictive Disorders, Paris, France.
Purpose: Alcohol use is a leading risk factor for preventable death, injury, and disease globally. Low sensitivity to the effects of alcohol is influenced by genes and predicts risk for harmful alcohol use and alcohol use disorder (AUD). Alcohol induces effects partly by modulation of gamma-aminobutyric acid receptors type A (GABARs).
View Article and Find Full Text PDFComparison of two strategies of glucocorticoid withdrawal in patients with rheumatoid arthritis in low disease activity (STAR): a randomised, placebo- controlled, double-blind trial.
Ann Rheum Dis
January 2025
Rheumatology Center, Toulouse University Hospital, Toulouse, France.
Objectives: To compare two strategies-a hydrocortisone replacement strategy and a prednisone tapering strategy-for their success in glucocorticoid discontinuation in patients with rheumatoid arthritis (RA) with low disease activity (LDA).
Methods: The Strategies for glucocorticoid TApering in Rheumatoid arthritis (STAR) study was a double- blind, double-placebo randomised controlled trial including patients with RA receiving a stable dose of glucocorticoid 5 mg/day for ≥3 months and were in LDA for ≥3 months. Patients were randomly assigned in a 1:1 ratio to either replace prednisone with 20 mg/day of hydrocortisone for 3 months, then reduce to 10 mg/day for 3 months before discontinuation or to taper prednisone by 1 mg/day every month until complete discontinuation, contingent on maintaining LDA.
Impacts of irrigation expansion on moist-heat stress based on IRRMIP results.
Nat Commun
January 2025
Department of Water and Climate, Vrije Universiteit Brussel, Brussels, Belgium.
Irrigation rapidly expanded during the 20 century, affecting climate via water, energy, and biogeochemical changes. Previous assessments of these effects predominantly relied on a single Earth System Model, and therefore suffered from structural model uncertainties. Here we quantify the impacts of historical irrigation expansion on climate by analysing simulation results from six Earth system models participating in the Irrigation Model Intercomparison Project (IRRMIP).
View Article and Find Full Text PDFAs in his earlier term, US President Donald Trump's misguided announcement that the US will withdraw from the Paris Agreement on climate continues a long history of confusion-mostly created intentionally-over the intersection of climate science and US climate policy. The tactics and consequences are no different from what opponents of climate science and action have been using for almost 50 years. For decades, political discourse on climate has blurred the lines between scientific reality and political ideology, treating established facts like debatable opinions, providing shifting reasons for making decisions, and turning what should be reasoned policy debates into ideological battlegrounds.
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