Many studies have displayed that freeze-thaw (F/T) conditioning is an environmentally friendly approach of improving sludge dewaterability. However, Initial water content (IWC) has a strong influence on the efficiency of the F/T method in conditioning sludge dewatering performance. Finding the most suitable F/T parameters for sludge with different IWCs is a critical issue that needs to be solved. Therefore, the coupled effects of different IWCs, refrigeration temperatures and the number of F/T cycles on sludge dewatering characteristics were explored. Single and multiple F/T cycles were performed on sludge from each group of IWCs at the same temperature. The coupling mechanism was analyzed by comparing the changes in sludge dewatering capacity before and after conditioning. The outcomes show that the F/T method is more suitable for sludge with a higher IWC. At -28 °C, the specific resistance to filtration of sludge with 87.5% IWC was reduced to 65.8 × 10 m/kg, and the post-filtration water content was only 63.1%. After repeated F/T cycles, the water content of the sludge gradually decreased, and the post-filtration water content of sludge with 87.5% IWC dropped to 58.8% after 7 cycles. Appropriate refrigeration temperatures can improve the effectiveness of ice crystal cracking, especially for sludge with a water content of less than 82.5%. The results of research provide a guide for the selection of F/T parameters in the operation of deep dewatering of sludge with different IWCs.
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http://dx.doi.org/10.1016/j.envres.2025.120970 | DOI Listing |
Sci Rep
January 2025
Department of Orthopaedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan.
While silk fibroin (SF) obtained from silkworm cocoons is expected to become a next-generation natural polymer, a fabrication method for SF-based artificial nerve conduits (SFCs) has not yet been established. Here, we report a bioresorbable SFC, fabricated using a novel freeze-thaw process, which ensures biosafety by avoiding any harmful chemical additives. The SFC demonstrated favorable biocompatibility (high hydrophilicity and porosity with a water content of > 90%), structural stability (stiffness, toughness, and elasticity), and biodegradability, making it an ideal candidate for nerve regeneration.
View Article and Find Full Text PDFMethods Mol Biol
January 2025
Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, Busan, Republic of Korea.
Marine invertebrates such as sponges, cnidarians, bryozoans, and tunicates are considered to be prolific sources of novel biologically active natural products. Specimens from these organisms are composed of soft tissues with a high water and inorganic salt content compared to those from terrestrial counterparts. In addition, some of the secondary metabolites from these organisms tend to be more polar than those of terrestrial.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
State Key Laboratory of Meat Quality Control and Cultured Meat Development, Key Laboratory of Meat Processing, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Cultured meat aims to produce meat mass by culturing cells and tissues based on the muscle regeneration mechanism, and is considered an alternative to raising and slaughtering livestock. Hydrogel building blocks are commonly used as substrates for cell culture in tissue engineering and cultured meat because of their high water content, biocompatibility, and similar three-dimensional (3D) environment to the cellular niche . With the characteristics of precise manipulation of fluids, microfluidics exhibits advantages in the fabrication of building blocks with different structures and components, which have been widely applied in tissue regeneration.
View Article and Find Full Text PDFEnviron Res
January 2025
Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc City, Ho Chi Minh City 700000, Viet Nam. Electronic address:
Many studies have displayed that freeze-thaw (F/T) conditioning is an environmentally friendly approach of improving sludge dewaterability. However, Initial water content (IWC) has a strong influence on the efficiency of the F/T method in conditioning sludge dewatering performance. Finding the most suitable F/T parameters for sludge with different IWCs is a critical issue that needs to be solved.
View Article and Find Full Text PDFBone
January 2025
Weldon School of Biomedical Engineering, Purdue University, Indianapolis, IN, United States; Roudebush Veterans Administration Medical Center, Indianapolis, IN, United States. Electronic address:
Comorbid diabetes and chronic kidney disease create a complex disease state with multi-faceted impacts on bone health, primarily reduced bone mass and tissue quality. To reduce fracture risk in this growing population, interventions are needed that target both bone mass and quality. Romosozumab (Romo) is an FDA-approved sclerostin inhibitor that has been shown to increase bone mass and strength in a murine model of combined diabetes and CKD (DKD), while Raloxifene (RAL) is a mild anti-resorptive used to treat osteoporosis that has also been shown to increase bone mechanical properties by increasing bone bound water content.
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