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The EP3622 Clone of CD1a for Diagnosing Intestinal Leishmaniasis in an Acquired Immunodeficiency Syndrome Patient in Colombia.
Travel Med Infect Dis
January 2025
Servicio de Infectología, Hospital Militar Central, Bogotá D.C., Colombia; Facultad de Medicina, Universidad Militar Nueva Granada, Bogotá, D.C., Colombia. Electronic address:
Evaluating CD1a Immunohistochemistry for Tegumentary Leishmaniasis Diagnosis in the New World: A Focus on Colombia.
Am J Dermatopathol
October 2024
Instituto Colombiano de Medicina Tropical- Universidad CES, Medellín, Colombia.
Introduction: Leishmaniasis, a chronic vector-borne disease caused by parasites of the genus Leishmania, presents diagnostic challenges. Conventional diagnostic methods struggle with accurate visualization of these parasites. Immunostaining with CD1a has demonstrated effectiveness in visualizing Leishmania parasites, particularly in the Old World.
View Article and Find Full Text PDFDiagnostic usefulness of immunohistochemical evaluation of CD1a antigen and polyclonal anti-leishmania antibodies in cutaneous leishmaniasis.
Histol Histopathol
May 2021
Department of Dermatology, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain.
Background: Different immunohistochemical markers to detect amastigotes in cutaneous leishmaniasis have been proposed with variable diagnostic usefulness.
Objectives: To evaluate the diagnostic usefulness of immunohistochemical amastigotes identification by specific polyclonal anti-Leishmania antibodies and CD1a expression (clone EP3622) in a series of PCR confirmed cutaneous leishmaniasis.
Materials And Methods: Thirty-three skin samples corresponding to PCR confirmed cutaneous leishmaniasis were included in the study.
The EP3622 clone of CD1a in the diagnosis of cutaneous leishmaniasis.
J Cutan Pathol
July 2020
Division of Anatomical Pathology, Department of Pathology, Queen Elizabeth II Health Sciences Centre, Nova Scotia Health Authority, Central Zone, Halifax, Nova Scotia, Canada.
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