We have studied copper-catalyzed cross-coupling of chiral α-CF-substituted allylboronic acids with α-diazoketones. The reaction proceeds with excellent regioselectivity and stereoselectivity via allylic rearrangement. The method is useful for formation a new allylic C(sp)-C(sp) bond with high selectivity. The poor yield is a limitation of this reaction.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.4c02869 | DOI Listing |
Publication Analysis
Top Keywords
copper-catalyzed cross-coupling
8
stereoselective copper-catalyzed
4
cross-coupling α-cf-allylboronic
4
α-cf-allylboronic acids
4
acids diazoketones
4
diazoketones studied
4
studied copper-catalyzed
4
cross-coupling chiral
4
chiral α-cf-substituted
4
α-cf-substituted allylboronic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!