Can estazolam plus remimazolam as an anxiolytic reduce remifentanil-induced postoperative hyperalgesia?

Minerva Anestesiol

Department of Anesthesiology and Reanimation, Karadeniz Technical University, Trabzon, Türkiye -

Published: January 2025

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http://dx.doi.org/10.23736/S0375-9393.24.18758-5DOI Listing

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Objective: This study aimed to investigate the effects of combining remimazolam with estazolam on hemodynamics and pain levels after laparoscopic gastrointestinal surgery.

Methods: A total of 184 patients who underwent laparoscopic gastrointestinal surgery were enrolled in this double-blind randomized controlled trial. The patients were divided into four groups: Study Group 1(Remimazolam), Study Group 2(Estazolam), Study Group 3(Remimazolam + Estazolam), and Control Group.

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