Herein, we present the development and evaluation of a molecularly imprinted polymer (MIP) sensor for the sensitive and selective detection of -nitrosodimethylamine (NDMA) in aqueous environments. MIP coatings over electrochemically active electrodes enable NDMA detection with a notably low detection limit of 1.16 ppb. Our findings demonstrate that the dual-monomer system employed in the MIP fabrication enhances both the selectivity and sensitivity toward NDMA. Additionally, the reversibility of the sensor was confirmed via a chronoamperometry regeneration process. Furthermore, the sensor's robustness was demonstrated across various water samples, as well as on different electrode materials, highlighting its potential for practical and reliable water quality monitoring applications.
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http://dx.doi.org/10.1021/acssensors.4c02462 | DOI Listing |
ACS Sens
January 2025
Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Herein, we present the development and evaluation of a molecularly imprinted polymer (MIP) sensor for the sensitive and selective detection of -nitrosodimethylamine (NDMA) in aqueous environments. MIP coatings over electrochemically active electrodes enable NDMA detection with a notably low detection limit of 1.16 ppb.
View Article and Find Full Text PDFAnal Chem
January 2025
The Education Ministry Key Lab of Resource Chemistry, Joint International Research Laboratory of Resource Chemistry, Ministry of Education, Shanghai Frontiers Science Center of Biomimetic Catalysis, Shanghai Key Laboratory of Rare Earth Functional Materials, College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China.
Conventional dual-signal electrochemiluminescence (ECL) sensors feature high sensitivity and reliability, but the involvement of coreactants inevitably results in a complex configuration and shows reproducibility risk. Here, we propose an exogenous coreactant-free dual-signal platform, comprising luminol (anodic luminophore), CdSe quantum dots (cathodic luminophore), and CoO/TiC electrocatalyst (coreaction promoter). At different redox potentials, CoO/TiC induces water oxidation and oxygen reduction to produce OH and O radicals, which subsequently drive cathodic and anodic ECL emission, respectively.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand.
Carcinoembryonic antigen (CEA) and C-reactive protein (CRP) are biomacromolecules known as cancer and inflammatory markers. Thus, they play a crucial role in early cancer diagnosis, post-treatment recurrence detection, and tumor risk assessment. This paper describes the development of an ultrasensitive and selective imprinted paper-based analytical device (PAD) as impedance sensor for determination of CEA and CRP in serum samples for point-of-care testing (POCT).
View Article and Find Full Text PDFFood Chem
January 2025
Key Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province, College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin 150025, PR China. Electronic address:
In this study, we designed a molecularly imprinted electrochemical sensor based on the reduced graphene oxide/polydopamine@Mxene (RPM) and FeCu-MOF for the detection of antiviral drug ribavirin (RBV). The RPM composite enhances the active surface area and electron transport capacity of the sensor, and the incorporation of FeCu-MOF can not only further improve the catalytic performance of the material, but also enables the sensor to harness the electrical reduction signal of HO. Furthermore, we developed an optimized molecularly imprinted polymer via density functional theory (DFT) to enhance the sensor's specificity and sensitivity for RBV detection.
View Article and Find Full Text PDFEnviron Toxicol Chem
January 2025
School of Energy and Environmental Engineering, University of Science and Technology Beijing, 100083China.
Phthalates, known as phthalate esters (PAEs), are among the most ubiquitous pervasive env7ironmental endocrine disruptors (EEDs), extensively utilized globally in various facets of modern life due to their irreplaceable role as plasticizers. The exponential production and utilization of plastic goods have substantially escalated plastic waste accumulation. Consequently, PAEs have infiltrated the environment, contaminating food and drinking water reservoirs, posing notable threats to human health.
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