Background: The occurrence of periprosthetic femoral fractures (PFFs) in cementless total hip arthroplasty (THA) might be associated with the proximal femoral morphology and the pelvis. PFFs in short stem THA are associated with an increased Canal Flare Index. PFFs in straight stem THA show a decreased Canal Flare Index. Therefore, this study aims to compare the femoral and pelvic geometry in PFFs between short stem and straight stem THA.
Methods: A retrospective comparative propensity-score matched study was performed. An institutional database of 5358 THAs was screened for early PFFs within the first 90 days after surgery. All cases of 136 PFFs in primary cementless THA were collected and matched, resulting in 67 PFFs in the straight stem and 37 PFFs in the short stem group. Both groups were analyzed regarding several parameters for femoral and pelvic morphology.
Results: A significantly lower distance from the anterior superior iliac spine to the greater trochanter (AGT) was detected in the straight stem group (96.4 vs. 104.8 mm, p = 0.024). All other femoral and pelvic parameters did not differ between both groups. Postoperative Vancouver A PFFs were significantly higher in straight stem THA, while postoperative Vancouver B PFFs were significantly higher in short stem THA.
Conclusion: The morphology of the proximal femur and the pelvis do not differ in several radiological parameters in patients sustaining a PFF between cementless short stem implanted via an anterolateral approach and straight stem THA implanted via a transgluteal approach. While there are differences in the Vancouver types of PFFs, these differences do not reflect any difference in the morphology of the proximal femur and the pelvis.
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http://dx.doi.org/10.1186/s13018-025-05502-y | DOI Listing |
J Orthop Surg Res
January 2025
Department for Orthopedics and Traumatology, Kepler University Hospital GmbH, Krankenhausstrasse 9, 4020, Linz, Austria.
Background: The occurrence of periprosthetic femoral fractures (PFFs) in cementless total hip arthroplasty (THA) might be associated with the proximal femoral morphology and the pelvis. PFFs in short stem THA are associated with an increased Canal Flare Index. PFFs in straight stem THA show a decreased Canal Flare Index.
View Article and Find Full Text PDFEur Urol Open Sci
January 2025
Clinical Institute, University of Southern Denmark, Odense, Denmark.
Background And Objective: We evaluated the effectiveness of injecting autologous adipose-derived regenerative cells (ADRCs) into plaque in men with chronic Peyronie's disease (PD).
Methods: This pilot safety study recruited 22 Danish men with chronic PD from an outpatient clinic. Patients received one bolus of ADRCs injected into plaque, with follow-ups at 1, 3, 6, and 12 mo.
Protoplasma
January 2025
Laboratory of Plant Anatomy and Morphology, Komarov Botanical Institute of the Russian Academy of Sciences, Professor Popov Street, 2, 197376, St. Petersburg, Russia.
Previously, it was found that four types of glandular trichomes (GTs) are developed on the surface of all aerial organs in Doronicum species. A detailed study of leaves had shown that only two types of GTs form in them. Nothing was known about any differences of GTs on vegetative and reproductive organs.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Induced pluripotent stem cell (iPSC)-derived neurons (iNs) have been widely used as models of neurodevelopment and neurodegenerative diseases. Coating cell culture vessels with extracellular matrixes (ECMs) gives structural support and facilitates cell communication and differentiation, ultimately enhances neuronal functions. However, the relevance of different ECMs to the natural environment and their impact on neuronal differentiation have not been fully characterized.
View Article and Find Full Text PDFHum Reprod
January 2025
IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III-Paul Sabatier (UPS), Toulouse, France.
Study Question: Does a human fallopian tube (HFT) organoid model offer a favourable apical environment for human sperm survival and motility?
Summary Answer: After differentiation, the apical compartment of a new HFT organoid model provides a favourable environment for sperm motility, which is better than commercial media.
What Is Known Already: HFTs are the site of major events that are crucial for achieving an ongoing pregnancy, such as gamete survival and competence, fertilization steps, and preimplantation embryo development. In order to better understand the tubal physiology and tubal factors involved in these reproductive functions, and to improve still suboptimal in vitro conditions for gamete preparation and embryo culture during IVF, we sought to develop an HFT organoid model from isolated adult stem cells to allow spermatozoa co-culture in the apical compartment.
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