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Toward an immunology-based classification of pain disorders?
Pharmacol Res
January 2025
Department of Surgical Sciences, Clinical Pain research, Uppsala University, Sweden.
Effects of Preoperative Oral Carbohydrate Loading on Neutrophil/Lymphocyte Ratio and Postoperative Complications following Colorectal Cancer Surgery: A Randomized Controlled Study.
Eur Surg Res
June 2023
Clinic of Anaesthesiology, Resuscitation and Intensive Care, University Clinical Center Tuzla, University of Tuzla, Faculty of Medicine, Tuzla, Bosnia and Herzegovina.
Introduction: Preoperative carbohydrate oral (CHO) drinks attenuate the surgical stress response; however, the effects of CHO supplementation on the neutrophil-to-lymphocyte ratio (NLR) as an inflammatory and immunology-based predictor remain unclear. This study evaluated the effects of preoperative CHO loading on NLR values and complications following open colorectal surgery compared with a conventional fasting protocol.
Methods: Sixty eligible participants having planned for routine and open colorectal cancer surgery from May 2020 to January 2022 were prospectively and randomly allocated to either the control (fasting) group, whose members discontinued oral intake beginning the midnight before surgery, or the intervention (CHO) group, whose members consumed a CHO solution the night before surgery and 2 h prior to anaesthesia.
Recent developments in detection and enumeration of waterborne bacteria: a retrospective minireview.
Microbiologyopen
December 2016
Department of Biological Sciences, Birla Institute of Technology and Science, Pilani-K.K. Birla Goa Campus, NH17B Bypass, Zuarinagar, Goa, 403726, India.
Waterborne diseases have emerged as global health problems and their rapid and sensitive detection in environmental water samples is of great importance. Bacterial identification and enumeration in water samples is significant as it helps to maintain safe drinking water for public consumption. Culture-based methods are laborious, time-consuming, and yield false-positive results, whereas viable but nonculturable (VBNCs) microorganisms cannot be recovered.
View Article and Find Full Text PDFKidney transplantation, bioengineering and regeneration: an originally immunology-based discipline destined to transition towards ad hoc organ manufacturing and repair.
Expert Rev Clin Immunol
November 2016
a Department of Surgery , Wake Forest University, Winston Salem , NC , USA.
Kidney transplantation (KT), as a modality of renal replacement therapy (RRT), has been shown to be both economically and functionally superior to dialysis for the treatment of end-stage renal disease (ESRD). Progress in KT is limited by two major barriers: a) a chronic and burgeoning shortage of transplantable organs and b) the need for chronic immunosuppression following transplantation. Although ground-breaking advances in transplant immunology have improved patient survival and graft durability, a new pathway of innovation is needed in order to overcome current obstacles.
View Article and Find Full Text PDFHistory of primary immunodeficiency diseases.
Curr Opin Allergy Clin Immunol
December 2012
Department of Pediatrics, University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, Washington 98101, USA.
Purpose Of Review: This issue of Current Opinion in Allergy and Clinical Immunology is focused on primary immunodeficiency diseases (PIDs). Like every disorder, PID has its own specific history, starting with the discovery of agammaglobulinemia in 1952 and still expanding at a rapid pace, covering, at the time of this publication, more than 180 genetically determined disorders. However, as this report attempts to demonstrate, the history of PID is intertwined with the development of modern medicine and is the direct result of the innovative thinking of physician scientists who introduced new concepts in pathology, microbiology, biochemistry, and immunology, based on carefully designed experiments.
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