Background And Objectives: Insomnia symptoms are more prevalent in older age and may be impacted by negative perceptions of aging; however, more research is needed. The present study characterizes the relationship between negative aging stereotypes and clinical insomnia symptoms in a nationally representative sample of older United States (U.S.) veterans.
Research Design And Methods: Data were analyzed from 3,000 U.S. veterans (aged 60-99) who participated in the National Health and Resilience in Veterans Study (NHRVS). Multivariable regression analyses were conducted to examine associations between negative aging stereotypes (assessed with the Expectations Regarding Aging Scale) and clinical insomnia (assessed with the Insomnia Severity Index).
Results: A total of 213 veterans (7.1%) screened positive for clinical insomnia and scored significantly higher on measures of negative emotional (p<.001), physical (p=.003), and cognitive (p=.013) aging stereotypes relative to veterans without clinical insomnia. Multivariable regression analyses revealed that, after adjusting for covariates, greater endorsement of negative stereotypes regarding emotional aging was associated with significantly greater odds of screening positive for clinical insomnia (OR=1.56, 95%CI=1.26-1.95, p<.001), sleep disturbance (OR=1.49, 95%CI=1.25-1.77, p<.001) and daytime dysfunction (OR=1.58, 95%CI=1.34-1.88, p<.001). Veterans who 'somewhat' and 'fully' endorsed these negative stereotypes were 3- and 6-times more likely to screen positive for clinical insomnia, respectively (probabilities=0.110 and 0.246 vs. 0.040).
Discussion And Implications: Negative aging stereotypes, particularly those related to emotional aging, are independently associated with clinical insomnia in older U.S. veterans. Efforts to modify these stereotypes in older veterans may help improve overall sleep quality.
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http://dx.doi.org/10.1093/geront/gnaf036 | DOI Listing |
Pharmacopsychiatry
January 2025
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
The United States Food and Drug Administration approved the xanomeline-trospium combination in September 2024 for treating schizophrenia, based in part on three double-blind, randomized placebo-controlled trials in adults with schizophrenia experiencing acute psychosis. This random-effects model pairwise meta-analysis of those three trials found that xanomeline-trospium was comparable to placebo in terms of all-cause discontinuation, discontinuation rate due to adverse events, Simpson-Angus Scale score change, Barnes Akathisia Rating Scale score change, body weight change, body mass index change, blood pressure change, serum total cholesterol change, blood glucose change, QTc interval changes, and the incidence of headache, somnolence, insomnia, dizziness, akathisia, agitation, tachycardia, gastroesophageal reflux disease, diarrhea, increased weight, and decreased appetite. However, xanomeline-trospium was associated with a higher incidence of at least one adverse event, dry mouth, hypertension, nausea, vomiting, dyspepsia, and constipation, and increased serum triglyceride compared with placebo.
View Article and Find Full Text PDFGerontologist
January 2025
U.S. Department of Veterans Affairs National Center for PTSD, VA Connecticut Healthcare System, West Haven, CT, USA.
Background And Objectives: Insomnia symptoms are more prevalent in older age and may be impacted by negative perceptions of aging; however, more research is needed. The present study characterizes the relationship between negative aging stereotypes and clinical insomnia symptoms in a nationally representative sample of older United States (U.S.
View Article and Find Full Text PDFTransl Psychiatry
January 2025
Department of Radiology, Shenzhen Nanshan People's Hospital, Taoyuan AVE 89, Nanshan district, Shenzhen, 518000, People's Republic of China.
At least 227 combinations of symptoms meet the criteria for Major Depressive Disorder (MDD). However, in clinical practice, patients consistently present symptoms in a regular rather than random manner, and the neural basis underlying the MDD subtypes remains unclear. To help clarify the neural basis, patients with MDD were clustered by symptom combinations to investigate the neural underpinning of each subtype using functional resonance imaging (fMRI).
View Article and Find Full Text PDFJ Dent Sci
January 2025
Department of Oral Medicine, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Background/purpose: Chewing difficulty can contribute to psychological stress, which reduces the quality of life for older adults. The purpose of this study was to investigate and analyze the severity of masticatory discomfort, stress response, and sleep disturbance in older patients experiencing masticatory discomfort due to tooth loss or temporomandibular disorders (TMD), to find the further treatment direction for these patients.
Materials And Methods: A total of 392 patients aged 50 years and older with mastication difficulties were analyzed.
J Clin Sleep Med
January 2025
Center for Sleep Medicine, Mayo Clinic, Rochester, MN.
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