Introduction: Single-stage bilateral cleft lip repair may require preoperative naso-alveolar molding (NAM) to decrease cleft widths and reposition the premaxilla. Staged operations may be performed in centers or regions without easy access to NAM. This retrospective study aims to examine the national prevalence of single-stage and staged bilateral cleft lip repairs over the past 23 years.
Methods: This retrospective study used TriNetX, a national deidentified aggregate database. The study used CPT codes to identify patients younger than 12 months who underwent single-stage (CPT-40701) or staged (CPT-40702) operation for bilateral cleft lip repair between 1/1/2000 to 9/16/2023. Patients were categorized by the year of their cleft lip repair. Patient demographics were analyzed through TriNetX. Linear regression analysis was conducted using PRISM software.
Results: Of the 1303 patients who underwent bilateral cleft lip repair, 57 patients were billed for both operations and were excluded from the analysis. In the remaining cohort, 1136 (91%) patients had a single-stage, and 110 (9%) had a staged bilateral cleft lip repair. No significant demographic differences were found between the 2 groups.The incidence of staged operations increased from 0 patients in 2000 to 14 patients in 2022. The incidence of single-stage operations increased from 6 patients in 2000 to 81 patients in 2022. Staged operations were rare in the first decade, accounting for 2% (n=5) of all bilateral cleft lip repairs between 2000 and 2011. The prevalence of staged operations showed a positive linear correlation (R2=0.75, P<0.0001) over the 23-year period, rising from 0% (n=0) in 2000 to 17% (n=12) in 2023.
Conclusion: Most bilateral cleft lip repairs have remained single-stage operations; however, staged approaches have also increased in popularity. This could indicate that NAM is less effective in patients with wide, severe bilateral cleft lip and palate, and surgeons may need to rely on a 2-stage approach for these patients.
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http://dx.doi.org/10.1097/SCS.0000000000011035 | DOI Listing |
Diabetol Metab Syndr
January 2025
The Centre for Cleft Lip and Palate Treatment, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Badachu Road, Shijingshan District, Beijing, 100144, People's Republic of China.
Background: Adipose tissue plays a critical role in the development of metabolically unhealthy obesity (MUO), with distinct adipose depots demonstrating functional differences. This study aimed to investigate the unique characteristics of subcutaneous (SA) and visceral adipose tissue (VA) in MUO.
Methods: Paired omental VA and abdominal SA samples were obtained from four male patients with MUO and subjected to Four-Dimensional Data Independent Acquisition (4D-DIA) proteomic and lysine acetylation (Kac) analyses.
BMC Oral Health
January 2025
Dentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy.
Introduction: Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition of oral bacterial flora, while the second analyzes data on dental caries.
Materials And Methods: Four databases (PubMed, Cochrane, Scopus, Web of Science) were searched for studies that compared periodontal parameters, caries index, and microbiota composition between persons with cleft lip and/or palate and healthy controls.
Codas
January 2025
Programa de Pós-Graduação em Fonoaudiologia, Universidade Estadual Paulista "Júlio de Mesquita Filho" - UNESP - Marília (SP), Brasil.
Purpose: To investigate whether there is a difference in the classification of speech hypernasality by inexperienced listeners using different ordinal scales; to verify the agreement of the listeners in the analyses when using these scales; and to verify whether the order in which the scales are presented influences the results.
Methods: Twenty Speech-Language Pathology students classified the degrees of hypernasality of 40 (oral) samples from patients with cleft lip and palate. Ten performed the classifications using a 4-point scale (absent, mild, moderate, and severe) and, after two weeks, using a 3-point scale (absent, slightly hypernasal, and very hypernasal).
Codas
January 2025
Universidade Vale do Rio Doce - UNIVALE - Governador Valadares (MG), Brasil.
Purpose: To promote orientation about cleft lip and palate and to verify knowledge and satisfaction of an orientation program through a website developed for students and health professionals.
Methods: This is a cross-sectional study, 13 healthcare professionals and 81 students from the areas of nursing, speech-language pathologist, medicine, nutrition, dentistry, and psychology participated. The research consisted of three stages: filling out a pre-program questionnaire, accessing the website (http://fissuralabiopalatina.
J Craniofac Surg
January 2025
Department of Pediatric Plastic Surgery, Children's Hospital Colorado, Aurora, CO.
Introduction: Single-stage bilateral cleft lip repair may require preoperative naso-alveolar molding (NAM) to decrease cleft widths and reposition the premaxilla. Staged operations may be performed in centers or regions without easy access to NAM. This retrospective study aims to examine the national prevalence of single-stage and staged bilateral cleft lip repairs over the past 23 years.
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