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Non-invasive in vitro NAM for the detection of reversible and irreversible eye damage after chemical exposure for GHS classification purposes (ImAi).
Arch Toxicol
January 2025
Translational Center Regenerative Therapies (TLC-RT), Fraunhofer Institute for Silicate Research (ISC), Röntgenring 12, 97070, Würzburg, Germany.
The potential risk of chemicals to the human eye is assessed by adopted test guidelines (TGs) for regulatory purposes to ensure consumer safety. Over the past decade, the Organization for Economic Co-operation and Development (OECD) has approved new approach methodologies (NAMs) to predict chemical eye damage. However, existing NAMs remain associated with limitations: First, no full replacement of the in vivo Draize eye test due to limited predictability of severe/mild damage was reached.
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- Infants with neonatal opioid withdrawal syndrome (NOWS) cared for using the Eat, Sleep, Console (ESC) approach experienced less medication treatment and shorter hospital stays compared to those receiving usual care.
- The study aimed to compare feeding practices and weight change in infants treated with ESC versus usual care across 26 hospitals in the US.
- Results showed that a higher percentage of infants in the ESC group were breastfed and received exclusive breast milk, indicating a more favorable feeding outcome compared to the usual care group.
Informed consent for national registration of COVID-19 vaccination caused information bias of vaccine effectiveness estimates mostly in older adults: a bias correction study.
J Clin Epidemiol
October 2024
Center for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Objectives: Registration in the Dutch national COVID-19 vaccination register requires consent from the vaccinee. This causes misclassification of nonconsenting vaccinated persons as being unvaccinated. We quantified and corrected the resulting information bias in vaccine effectiveness (VE) estimates.
View Article and Find Full Text PDF[Vaccination against influenza, pneumococcus and herpes zoster in the elderly Survey of prescribing physicians: assessment of knowledge and identification of obstacles to the prescription of vaccination].
Geriatr Psychol Neuropsychiatr Vieil
September 2023
Département de gérontologie clinique, CHU de Saint-Étienne, France, Chaire santé des aînés, UniversitéJean-Monnet, Saint-Étienne, France, Gérontopôle Auvergne Rhône-Alpes,Saint-Étienne, France.
Vaccination coverage is insufficient for influenza, pneumococcus, and herpes zoster in people over the age of 65 in France, even though these are common infectious diseases. Using a computerised questionnaire, the aim of our study was to assess the knowledge of general practitioners, geriatricians, infectious diseases specialists and interns in the Loire region about the vaccination against these three diseases in elderly subjects, to identify the obstacles to vaccination, and to evaluate whether the provision of knowledge modifies the prescriptions and vaccination recommendations made to patients. Of the 125 responses from doctors and interns, 90.
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