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Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage.
Pediatr Res
January 2025
Department of Pediatrics, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI, USA.
Background: The immune heterogeneity of biliary atresia (BA) presents a challenge for development of prognostic biomarkers. This study aimed to identify early immune signatures associated with biliary drainage after Kasai Portoenterostomy (KPE).
Methods: Serum samples, liver slides, and clinical data were obtained from patients enrolled in the NIDDK-supported Childhood Liver Disease Research Network.
Is the treatment of ankle osteoarthritis changing over time in Italy? Analysis of temporal trends for fusion and arthroplasty in a population-based study from 2001 to 2022 on the National Hospital Discharge Record database.
J Orthop Traumatol
January 2025
Italian National Registry of Implantable Prostheses (RIPI), Italian National Institute of Health, Viale Regina Elena 299, 00161, Rome, Italy.
Background: Treatment of ankle osteoarthritis by total ankle replacement (TAR) is increasing worldwide. The aim of the study was to present the overall temporal trends of TAR throughout 22 years (2001-2022) in Italy, analyzing the distributions of hospitals by volume of activity and patients by age and sex, drawing on the National Hospital Discharge Record database. Furthermore, as a secondary aim, we compared these trends with those of ankle fusions.
View Article and Find Full Text PDFAcute appendicitis and its treatment: a historical overview.
Int J Colorectal Dis
January 2025
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Purpose: Acute appendicitis (AA) is the leading cause of acute abdomen worldwide, with an incidence of 90-100 cases per 100,000 individuals annually and a lifetime risk of 7-12%. Despite its prevalence, historical accounts of AA are limited, particularly when compared to conditions like haemorrhoids, likely due to the appendix's internal location. This article traces the historical evolution of AA treatment from ancient times to the present, highlighting key contributions.
View Article and Find Full Text PDFUpskilling or deskilling? Measurable role of an AI-supported training for radiology residents: a lesson from the pandemic.
Insights Imaging
January 2025
Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Objectives: This article aims to evaluate the use and effects of an artificial intelligence system supporting a critical diagnostic task during radiology resident training, addressing a research gap in this field.
Materials And Methods: We involved eight residents evaluating 150 CXRs in three scenarios: no AI, on-demand AI, and integrated-AI. The considered task was the assessment of a multi-regional severity score of lung compromise in patients affected by COVID-19.
Understanding Burnout among Surgical residents: a mixed method study.
Sci Rep
January 2025
General Psychology, Department of Psychology, Isfahan University, Isfahan, Iran.
Burnout is a complex condition that can strangely affect individuals in healthcare professions, such as surgeons and surgical residents. This study aimed to assess burnout and better explain the concept of burnout in surgical residents and the clarification strategies they take with this phenomenon to solve this problem. This mixed methods study was conducted at Shiraz University of Medical Sciences in 2022-2023 with two quantitative and qualitative phases.
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