Correction for 'Total syntheses of Kavaratamide A and 5--Kavaratamide A' by Tieshun Ren , , 2025, https://doi.org/10.1039/d4ob01409j.
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Correction: Total syntheses of Kavaratamide A and 5--Kavaratamide A.
Org Biomol Chem
January 2025
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300350, People's Republic of China.
Correction for 'Total syntheses of Kavaratamide A and 5--Kavaratamide A' by Tieshun Ren , , 2025, https://doi.org/10.1039/d4ob01409j.
View Article and Find Full Text PDFTotal syntheses of Kavaratamide A and 5--Kavaratamide A.
Org Biomol Chem
December 2024
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300350, People's Republic of China.
The total synthesis of Kavaratamide A, a new Linear Lipodepsipeptide from the Marine Cyanobacterium was achieved by assembling the side chain in stage through condensation coupling, carbon-chain extension, Steglich esterification and Evans aldol reaction. In addition, total synthesis of Kavaratamide A's isomer, 5--kavaratamide A, is also successfully achieved. Cytotoxicity test suggested that Kavaratamide A and 5--Kavaratamide A have a moderate bioactivity against cancer cells.
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