Neuroticism predicts behaviors symptomatic of behavior dysregulation. One idea is that Neuroticism encompasses deficits in executive functioning; despite this link being empirically substantiated, it remains poorly understood. If Neuroticism is associated with executive functioning deficits due to it activating impulsivity in response to negative emotion, and if Negative Urgency (NU) is the specific aspect of emotional impulsivity that amplifies impulsivity in response to negative emotion, then Neuroticism's link to executive functioning deficits should be enhanced in individuals higher in NU. A large representative sample of US adults ( = 446; = 46.10; 51.1% female; 78.0% White) completed validated measures of Neuroticism, NU and Positive Urgency (PU), and executive functioning deficits. As predicted, we found that Neuroticism's link to executive functioning deficits was moderated by NU (after controlling for PU) but not PU (after controlling for NU); specifically, Neuroticism's relation to executive functioning deficits was over twice as large for people with elevated (+1 SD) versus de-elevated (-1 SD) levels of NU. Furthermore, NU moderated relations between each Neuroticism facet (e.g., Anxiety, Anger) and executive functioning deficits. The findings extend understanding of how Neuroticism relates to executive functioning, suggesting utility in distinguishing between PU and NU and potentially studying Neuroticism and NU as interacting.
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http://dx.doi.org/10.1177/00332941251315655 | DOI Listing |
Mol Psychiatry
January 2025
Department of Psychiatry, University of Oxford, Oxford, UK.
Cognitive and neural mechanisms underlying bipolar disorder (BD) and its treatment are still poorly understood. Here we examined the role of adaptations in risk-taking using a reward-guided decision-making task. We recruited volunteers with high (n = 40) scores on the Mood Disorder Questionnaire, MDQ, suspected of high risk for bipolar disorder and those with low-risk scores (n = 37).
View Article and Find Full Text PDFSci Rep
January 2025
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
There are mixed findings regarding executive functioning in individuals born small for gestational age (SGA) at term and associations between performance-based and self-reported executive functions have yet to be examined in adults. In a prospective cohort study, 56 SGA and 68 non-SGA control participants were assessed at 32 years using the performance-based Trail Making Test (TMT) and the self-report questionnaire Behavior Rating Inventory of Executive Function - Adult Version (BRIEF-A). The SGA group used 1.
View Article and Find Full Text PDFObstet Gynecol Clin North Am
March 2025
Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:
The hormonal changes that accompany the transition to menopause are disruptive to most women, and for some, mental health maybe adversely affected. Depressive symptoms and major depression are the best-studied conditions in association with menopause, but anxiety, executive function, and comorbid pre-existing psychiatric conditions all influence the symptomatology that women will experience during this phase of their lives. The epidemiology, diagnosis, and evidence-based treatment guidelines for perimenopausal patients are discussed.
View Article and Find Full Text PDFBMJ Open
January 2025
Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Objective: Delayed neurocognitive recovery, previously known as postoperative cognitive dysfunction, is a common complication affecting older adults after surgery. This study aims to address the knowledge gap in postoperative neurocognitive recovery by exploring the relationship between subjective experiences, performance-based measurements, and blood biomarkers.
Design: Mixed-methods study with a convergent parallel (QUAL+quan) design.
Prog Neuropsychopharmacol Biol Psychiatry
January 2025
Department of Rehabilitation, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China; Department of Neurology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China; Department of Clinical Medical Research Center, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. Electronic address:
Cognitive decline is one of the most significant non-motor symptoms of Parkinson's disease (PD), with executive dysfunction (EDF) being the most prominent characteristic of PD-associated cognitive deficits. Currently, lack of uniformity in the conceptualization and assessment scales for executive functions impedes the early and accurate diagnosis of executive dysfunction in PD. The neurobiological mechanisms of executive dysfunction in PD remain poorly understood.
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