Purpose: The purpose of this work was to evaluate the image quality of a commercial CT scanner equipped with a novel detector and filtration technology called PureVision Optics (PVO).
Methods: CT number, noise, contrast-to-noise ratio (CNR), modulation transfer function (MTF), and noise power spectrum (NPS) were assessed using the ACR CT Accreditation phantom scanned with various acquisitions at 80 kV, 100 kV, 120 kV, and 135 kV, each with multiple CTDIvol values of 20 mGy, 40 mGy, and 65 mGy. Artifacts were evaluated in an anthropomorphic head phantom, a cadaver head, and in patient studies. Two neuroradiologists assessed image quality features in various patients who were examined with unenhanced brain CT on both scanners.
Results: Compared with the conventional scanner, for the same CTDIvol, the PVO scanner produced 20.3% less image noise (P < 0.001), 18.9% higher CNR (P < 0.01), and 24.6% higher spatial resolution (P < 0.001). Streak artifacts were less severe with the PVO scanner for the phantom, cadaver, and patient scans (P < 0.05). Radiologists scored the PVO scanner as significantly better for visualization of the cerebrospinal fluid space over the cerebral sulci in high convexity, image noise in gray and white matter, and artifacts in the posterior fossa. They also significantly preferred the PVO scanner for visualization of the border between brain gray and white matter, cerebrospinal fluid space around the mesencephalon, and overall diagnostic acceptability.
Conclusions: For matched CTDIvol values, the scanner equipped with PVO technology produced better objective and subjective image quality metrics in brain CT imaging compared with a conventional CT scanner without PVO. In clinical settings, PVO may allow for lower doses while enhancing imaging through dense areas, improving visualization of subtle details, and offering more effective options for examining obese patients.This research received financial support from Canon Medical Systems USA. The study design and data were fully controlled by the coauthors, of which none are employees or consultants of Canon Medical Systems USA.
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http://dx.doi.org/10.1097/RCT.0000000000001711 | DOI Listing |
J Comput Assist Tomogr
January 2025
Department of Radiology, College of Medicine, University of Florida, Gainesville, FL.
Purpose: This study evaluated beam quality and radiation dosimetry of a CT scanner equipped with a novel detector and filtration technology called PureVision Optics (PVO). PVO features miniaturized electronics, a detector cut with microblade technology, and increased filtration in order to increase x-ray detection and reduce image noise.
Methods: We assessed the performance of two similar 320-detector CT scanners: one equipped with PVO and one without.
J Comput Assist Tomogr
January 2025
Department of Radiology, College of Medicine, University of Florida, Gainesville, FL.
Purpose: The purpose of this work was to evaluate the image quality of a commercial CT scanner equipped with a novel detector and filtration technology called PureVision Optics (PVO).
Methods: CT number, noise, contrast-to-noise ratio (CNR), modulation transfer function (MTF), and noise power spectrum (NPS) were assessed using the ACR CT Accreditation phantom scanned with various acquisitions at 80 kV, 100 kV, 120 kV, and 135 kV, each with multiple CTDIvol values of 20 mGy, 40 mGy, and 65 mGy. Artifacts were evaluated in an anthropomorphic head phantom, a cadaver head, and in patient studies.
J Med Imaging (Bellingham)
January 2025
U.S. Food and Drug Administration, Office of Science and Engineering Labs, Division of Imaging, Diagnostics, and Software Reliability, Silver Spring, Maryland, United States.
Purpose: We evaluate the impact of charge summing correction on a cadmium telluride (CdTe)-based photon-counting detector in breast computed tomography (CT).
Approach: We employ a custom-built laboratory benchtop system using the X-THOR FX30 0.75-mm CdTe detector (Varex Imaging, Salt Lake City, Utah, United States) with a pixel pitch of 0.
Toxicol In Vitro
January 2025
Atomic Energy and Alternative Energies Commission (CEA), Laboratory of Radiotoxicology, CEA, Paris-Saclay University, Bruyères-le-Châtel, France.
Internal contamination by inhalation of plutonium poorly soluble compounds leads to their long time retention in alveolar macrophages inducing delayed pathology development. As previous studies highlighted co-localization of retained Pu and inflammatory lesions, this study was designed to assess the combined effect of the reference treatment (DTPA) and anti-inflammatory drugs on Pu-induced early response of macrophages in vitro. Pu colloids, mimicking poorly soluble Pu, were characterized using filtration and solid-state nuclear track detectors CR39.
View Article and Find Full Text PDFAppl Radiat Isot
March 2025
Department of Health and Safety Convergence Science, Korea University, Anam-ro 145, Seoul, 02841, Republic of Korea; Transdisciplinary Major in Learning Health System, Graduate School, Korea University, Seoul, 02841, Republic of Korea. Electronic address:
A 4π-field of view deep-learning-based collimator-less imaging system was designed with the Monte Carlo method and performance of the system was studied to verify the feasibility of system. A 4 × 4 × 4 voxelated single-volume GAGG(Ce) system and Co, Ba, Na, and Cs point sources at 2000 positions were modeled using Monte-Carlo N-particle transport code version 6 (MCNP6). Two types of the localized energy deposition acquired with a voxelated detector system with and without energy bins, were calculated.
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