Coats-like response refers to a condition where abnormal telangiectatic retinal vessels and aneurysms associated with subretinal exudation are seen in the setting of other ocular or systemic diseases. So far, it has been described with various ocular disorders like retinitis pigmentosa, chronic ischemic branch retinal vein obstruction and pars planitis. A man in his 30s presented with a 1-month history of diminution of vision in the left eye. On examination, the left eye fundus showed extensive subretinal exudation along with evidence of old and recent periphlebitis. Fluorescein angiography revealed multiple telangiectatic vessels and peripheral aneurysms along with perivenular leak. Optical coherence tomography of the macula demonstrated cystoid oedema with subretinal fluid. The case was diagnosed as Coats-like response with occlusive periphlebitis and was successfully managed with oral steroids alone.

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2024-263232DOI Listing

Publication Analysis

Top Keywords

coats-like response
12
response occlusive
8
subretinal exudation
8
left eye
8
unusual coats-like
4
occlusive retinal
4
retinal periphlebitis
4
periphlebitis coats-like
4
response refers
4
refers condition
4

Similar Publications

Coats-like response refers to a condition where abnormal telangiectatic retinal vessels and aneurysms associated with subretinal exudation are seen in the setting of other ocular or systemic diseases. So far, it has been described with various ocular disorders like retinitis pigmentosa, chronic ischemic branch retinal vein obstruction and pars planitis. A man in his 30s presented with a 1-month history of diminution of vision in the left eye.

View Article and Find Full Text PDF

Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids- a case report.

BMC Ophthalmol

January 2025

Dept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.

Purpose: To report a rare case of a Coats-like response developing after vitreoretinal surgery for proliferative diabetic retinopathy (PDR) and its successful management with retinal laser photocoagulation and adjunctive intravitreal steroids.

Case Description: A 52-year-old woman with a five-year history of type 2 diabetes mellitus and hypertension presented with decreased vision in the left eye (counting fingers at 1 m). Examination revealed high-risk PDR in both eyes, with a subtotal macula-off combined retinal detachment in the left eye.

View Article and Find Full Text PDF

To report a unique case of retinal exudation consistent with a Coats-like response and associated with mutations in , confirming the diagnosis of Poretti-Boltshauser syndrome. A case and its findings were analyzed. A 24-year-old woman presented with mild peripheral avascularity, circumferential membranes at the edge of the vascularized retina, exudation, numerous vessels with aneurysmal changes, and inferior retinal elevation in both eyes.

View Article and Find Full Text PDF

Coats-like Vasculopathy in Inherited Retinal Disease: Prevalence, Characteristics, Genetics, and Management.

Ophthalmology

December 2023

Moorfields Eye Hospital, London, United Kingdom; UCL Institute of Ophthalmology, University College London, London, United Kingdom. Electronic address:

Article Synopsis
  • This study focuses on a diverse group of 67 patients with inherited retinal disease (IRD)-related Coats-like vasculopathy (CLV), the largest cohort documented.
  • The research involved reviewing clinical and genetic data to assess visual function and treatment responses, revealing that 54% of patients had isolated retinitis pigmentosa and most presented with significant retinal issues like exudative retinal detachment.
  • Results showed a significant decline in visual acuity over time, with a considerable number of patients losing vision, highlighting the challenges in managing this condition.
View Article and Find Full Text PDF

Mutations in the apicobasal polarity gene CRB1 lead to diverse retinal diseases, such as Leber congenital amaurosis, cone-rod dystrophy, retinitis pigmentosa (with and without Coats-like vasculopathy), foveal retinoschisis, macular dystrophy, and pigmented paravenous chorioretinal atrophy. Limited correlation between disease phenotypes and CRB1 alleles, and evidence that patients sharing the same alleles often present with different disease features, suggest that genetic modifiers contribute to clinical variation. Similarly, the retinal phenotype of mice bearing the Crb1 retinal degeneration 8 (rd8) allele varies with genetic background.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!