In conclusion, the distinct evolution patterns of panzootic influenza A(H5Nx) compared to A(H1N1) and A(H3N2) complicate vaccine development. Effective strategies must consider these unique patterns and the impact of pre-existing immunity. Leveraging AI-based methods for optimized antigen design is essential to mitigate the potential impact of emerging antigenically variable strains and will provide valuable insights for developing more effective vaccines to prepare for future pandemics.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763911 | PMC |
| http://dx.doi.org/10.1016/j.xinn.2024.100739 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mycobacteriophages are viruses that specifically infect bacteria of the Mycobacterium genus. A substantial collection of mycobacteriophages has been isolated and characterized, offering valuable insights into their diversity and evolution. This collection also holds significant potential for therapeutic applications, particularly as an alternative to antibiotics in combating drug-resistant bacterial strains.
View Article and Find Full Text PDFCombined semiquantitative nail-enthesis complex ultrasonography and capillaroscopy in psoriasis and psoriatic arthritis.
Front Immunol
January 2025
Rheumatology Unit, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
This pilot study investigates distinctive features within the nail-enthesis complex among Psoriatic arthritis (PsA), Psoriasis (PSO), Rheumatoid Arthrit is (RA), and Healthy Control (HC) groups, utilizing a combined approach of ultrasound (US) and nailfold videocapillaroscopy (NVC). Clinical assessments and comprehensive US and NVC evaluations of the nail-enthesis complex were conducted on 72 subjects (18 PsA, 16 PSO, 19 RA, 19 HC). Unsupervised clustering models and factor analysis were employed to identify patterns and interrelationships between US and NVC parameters.
View Article and Find Full Text PDFCryptic genetic diversity and molecular detection of Trypanosoma theileri complex in the deer fly Chrysops dispar Fabricius from Thailand.
Trop Biomed
December 2024
Department of Biology, Faculty of Science, Mahasarakham University, Kantharawichai District, Mahasarakham 44150, Thailand.
The deer fly (Diptera, Tabanidae), Chrysops dispar Fabricius is a common and widespread pest and vector species transmitting pathogens to animals including economically significant livestock. However, there is only limited information on genetic diversity, which crucial for understanding disease epidemiology. In this study, we examined genetic diversity of C.
View Article and Find Full Text PDFMolecular identification and phylogenetic analysis of Anaplasma marginale and Anaplasma centrale isolated from commercial Mafriwal cattle in Johor, Malaysia.
Trop Biomed
December 2024
Department of Veterinary Paraclinical Study, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, 16100, Kota Bharu, Kelantan, Malaysia.
Bovine anaplasmosis is a tick-borne disease in cattle which is mainly caused by Anaplasma marginale and Anaplasma centrale. It poses significant economic burdens and threat on livestock industries worldwide. This study aimed to identify Anaplasma spp.
View Article and Find Full Text PDFTaWI12 may be involved in pistillody and leaf cracking in wheat.
BMC Plant Biol
January 2025
Triticeae Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
TaWI12 is a member of the wound-induced (WI) protein family, which has been implicated in plant stress responses and developmental processes. Wheat (Triticum aestivum L.) is a crucial staple crop upon which human sustenance relies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!