[This corrects the article DOI: 10.1039/D4RA06744D.].
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http://dx.doi.org/10.1039/d5ra90011e | DOI Listing |
Sci Transl Med
January 2025
Graduate Program in Human Genetics, University of Miami Miller School of Medicine, 1501 NW 10th Avenue (M-860), Miami, FL 33136, USA.
Primary mitochondrial disorders are most often caused by deleterious mutations in the mitochondrial DNA (mtDNA). Here, we used a mitochondrial DddA-derived cytosine base editor (DdCBE) to introduce a compensatory edit in a mouse model that carries the pathological mutation in the mitochondrial transfer RNA (tRNA) alanine (mt-tRNA) gene. Because the original m.
View Article and Find Full Text PDF[This corrects the article DOI: 10.1371/journal.pntd.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
University of Maryland, NIST, Joint Center for Quantum Information and Computer Science, /, College Park, Maryland 20742, USA.
Diatomic molecular codes [V. V. Albert, J.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Pediatrics, The Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York.
Importance: Pediatric obesity and hypertension are highly correlated. To mitigate both conditions, provision of counseling on nutrition, lifestyle, and weight to children with high blood pressure (BP) measurements is recommended.
Objective: To examine racial and ethnic disparities in receipt of nutrition, lifestyle, and weight counseling among patients with high BP at pediatric primary care visits stratified by patients' weight status.
HardwareX
March 2025
LIGHT Community, Physics Department, Imperial College London SW7 2AZ, UK.
We recently demonstrated polarisation differential phase contrast microscopy () as a robust, low-cost single-shot implementation of (semi)quantitative phase imaging based on differential phase microscopy. utilises a polarisation-sensitive camera to simultaneously acquire four obliquely transilluminated images from which phase images mapping spatial variation of optical path difference can be calculated. microscopy can be implemented on existing or bespoke microscopes and can utilise radiation at a wide range of visible to near infrared wavelengths and so is straightforward to integrate with fluorescence microscopy.
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