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Pterygium-like conjunctival nevus: a clinicopathological study.
Can J Ophthalmol
January 2025
Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Key Clinical and Histopathological Features of a Pterygium-Like Induced Lesion in a Rabbit Model.
Transl Vis Sci Technol
October 2024
Tecnologico de Monterrey, School of Medicine and Health Sciences, Monterrey, Mexico.
Purpose: Surgery is the definitive treatment for pterygium; therefore, reliable animal models are required for translational research. The goal of this investigation was to establish a standardized preclinical model of pterygium-like lesion.
Methods: A subconjunctival injection of fibroblasts (NIH3T3) and extracellular matrix was administered to 22 New Zealand rabbits.
Corneal Healing and Recovery of Ocular Crystallinity with a Dichloromethane Extract of D.C. in a Novel Murine Model of Ocular Pterygium.
Molecules
July 2021
Centro de Desarrollo de Productos Bióticos del Instituto Politécnico Nacional, Carretera Yautepec-Jojutla, Km. 6, Calle CEPROBI No. 8, Col. San Isidro, Yautepec C.P. 62731, Morelos, Mexico.
Pterygium is a corneal alteration that can cause visual impairment, which has been traditionally treated with the sap of D.C. The pharmacological effect of a dichloromethane extract of S.
View Article and Find Full Text PDFA case of pterygium-like proliferation containing postoperative limbal dermoid remnants: a clinicopathological study.
BMC Ophthalmol
January 2021
Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Background: This study reports a case of pterygium-like proliferation containing postoperative limbal dermoid remnants and its clinicopathological features.
Case Presentation: A 79-year-old Japanese woman, with a history of congenital limbal dermoid resection at age 12, presented with a pterygium-like tissue growth in the left eye. Its temporal location and marked thickness with abundant fatty droplets were atypical of primary pterygium.
Extracellular matrix and fibroblast injection produces pterygium-like lesion in rabbits.
Biol Res
June 2018
Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Ave. Morones Prieto 3000, 64710, Monterrey, NL, Mexico.
Background: Translational research to develop pharmaceutical and surgical treatments for pterygium requires a reliable and easy to produce animal model. Extracellular matrix and fibroblast are important components of pterygium. The aim of this study was to analyze the effect of the subconjunctival injection of fibroblast cells (NIH3T3 cell line) and exogenous extracellular matrix in rabbits in producing a pterygium-like lesion.
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