Investment in resources is essential for facilitating information dissemination in real-world contexts, and comprehending the influence of resource allocation on information dissemination is, thus, crucial for the efficacy of collaborative networks. Nonetheless, current studies on information dissemination frequently fail to clarify the complex interplay between information distribution and resources in network contexts. In this work, we establish a resource-based information dissemination model to identify the complex interplay by examining the propagation threshold and equilibriums. We assess the model's efficacy by juxtaposing the mean-field method with Monte Carlo simulations across three author collaboration networks. In addition, we define the function of resources in information dissemination and evaluate the model's applicability using propagating threshold, time evolution, and parametric analyses. Our findings indicate that an increase in available resources accelerates and expands the distribution of information. Notably, we identify abrupt transition phenomena concerning available resources and demonstrate that the information self-learning rate and the information review rate hasten this transition, while information decline and re-diffusion rates decelerate it.
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http://dx.doi.org/10.1063/5.0250482 | DOI Listing |
Anal Chem
January 2025
Rural Health Research Institute, Charles Sturt University, Orange, New South Wales 2800, Australia.
The detection and analysis of circulating cell-free nucleic acid (ccfNA) biomolecules are redefining a new era of molecular targeted cancer therapies. However, the clinical translation of electrochemical ccfNA biosensing remains hindered by unresolved challenges in analytical specificity and sensitivity. In this Perspective, we present a novel electrochemical framework for improving ccfNA biosensor performance by optimizing the critical electrode-biomolecules-electrolyte interfaces.
View Article and Find Full Text PDFmBio
January 2025
Department of Integrative Biology, University of California, Berkeley, Berkeley, California, USA.
The composition of the gut microbiome is determined by a complex interplay of diet, host genetics, microbe-microbe interactions, abiotic factors, and stochasticity. Previous studies have demonstrated the importance of host genetics in community assembly of the gut microbiome and identified a central role for DBL-1/BMP immune signaling in determining the abundance of gut . However, the effects of DBL-1 signaling on gut bacteria were found to depend on its activation in extra-intestinal tissues, highlighting a gap in our understanding of the proximal factors that determine microbiome composition.
View Article and Find Full Text PDFNurs Philos
January 2025
Ngarruwan Ngadju, University of Wollongong, Wollongong, Australia.
This article presents a conceptual analysis of the contemporary understanding of NURSING in Australia and proposes strategies for decolonisation. Through historical reflection and the lens of cultural safety and critical race theory, it examines some conditions which make up this concept, including "Florence Nightingale-influenced practices," "intellectual practitioners," and "whiteness in nursing." This analysis aims to identify conditions which we take to be necessary for the folk concept of NURSING to be satisfied and which result in negative outcomes.
View Article and Find Full Text PDFGerontologist
January 2025
School of Social Work, University of Texas at Arlington, Arlington, Texas, United States.
Background And Objective: Older adult refugees from Burma face unique challenges in third-country resettlement, yet their experiences are often overlooked in research and policy. This scoping review aims to examine the literature on refugees aged 45 and older from Burma in third-country resettlement contexts, identify factors contributing to successful integration, and elucidate the unique challenges they encounter.
Research Design And Methods: We systematically searched seven databases using Arksey and O'Malley's framework.
Autophagy
January 2025
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Postmitotic skeletal muscle critically depends on tightly regulated protein degradation to maintain proteomic stability. Impaired macroautophagy/autophagy-lysosomal or ubiquitin-proteasomal protein degradation causes the accumulation of damaged proteins, ultimately accelerating muscle dysfunction with age. While studies have demonstrated the complementary nature of these systems, their interplay at the organism levels remains poorly understood.
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