Unlabelled: TKA is routinely done orthopaedic procedure done that aims at improving the quality of patients' life by providing pain relief, functional improvement and deformity correction. This study aims to study the efficacy and safety of a Periarticular analgesic cocktail including ropivacaine injection and epidural ropivacaine for early rehabilitation after a total knee replacement.
Methods: Total of 100 patients divided into two groups, one group received epidural ropivacaine and second group given periarticular cocktail containing ropivacaine. Then postoperatively their pain score comparison using VAS score and their functional status is documented knee society score.
Results: The mean age for the epidural group is 60.28 years, while for the periarticular cocktail group it's 60.88 years. For female patients, 34 (68%) received epidural analgesia, while 24 (48%) received periarticular cocktail. Among male patients, 16 (32%) had epidural analgesia, and 26 (52%) received periarticular cocktail. For pre-operative pain scores, patients receiving Epidural analgesia had a slightly higher mean score of 7.24 compared to those receiving Periarticular Cocktail, who had a mean score of 7.12. Patients in the Epidural group had a higher mean knee flexion of 83.84 degrees compared to the Periarticular Cocktail group, which had a mean flexion of 79.36 degrees. The Knee Society Scores (KSS) for the post-operative scores; The Epidural group had a mean score of 80.16. The Periarticular Cocktail group had a mean score of 88.40.
Conclusion: In conclusion, this study supports the periarticular analgesic cocktail over epidural analgesia for pain management and early rehabilitation following TKR.
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Unlabelled: TKA is routinely done orthopaedic procedure done that aims at improving the quality of patients' life by providing pain relief, functional improvement and deformity correction. This study aims to study the efficacy and safety of a Periarticular analgesic cocktail including ropivacaine injection and epidural ropivacaine for early rehabilitation after a total knee replacement.
Methods: Total of 100 patients divided into two groups, one group received epidural ropivacaine and second group given periarticular cocktail containing ropivacaine.
Analgesic efficacy and safety of methylene blue combined with cocktail for periarticular infiltration following total knee arthroplasty: a prospective, randomized, controlled study.
Perioper Med (Lond)
January 2025
Department of Anesthesiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Objective: This study aims to explore the analgesic effects and safety of periarticular injections of methylene blue (MB) combined with a cocktail formulation following total knee arthroplasty (TKA).
Methods: A total of 70 patients undergoing total knee arthroplasty were selected and divided into two groups based on the cocktail formula used for periarticular infiltration, including the methylene blue group (M group, n = 35) and the control group (C group, n = 35). Both groups underwent spinal anesthesia.
Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial.
J Orthop Surg Res
November 2024
Department of Orthopaedics, Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, P.R. China.
Background: Periarticular local infiltration analgesia (LIA) has become a widely used method for postoperative pain management after unicompartmental knee arthroplasty (UKA). However, the efficacy of using magnesium sulphate or sodium bicarbonate in LIA cocktails during UKA is not yet clear. The present study aimed to evaluate whether the modified LIA has advantages in pain control and joint function recovery after UKA surgery.
View Article and Find Full Text PDFEffect of periarticular cocktail of analgesia on immediate post-operative clinical outcomes after bilateral simultaneous total knee arthroplasty: a randomized placebo controlled, split-body superiority trial.
J Clin Orthop Trauma
November 2024
Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, India.
Introduction: Total knee arthroplasty is the commonest procedure being done for Osteoarthritis of knee in current practice. In spite of its success many patients suffer from post-operative pain especially in the early post-operative period. The study aimed to evaluate the pain relief and functional benefit of periarticular cocktail infiltration.
View Article and Find Full Text PDFStudy of Efficacy of Extraosseous Local Infiltration of Multimodal Drug Cocktail for Pain Management After Total Joint Arthroplasty in Lower Limb.
Cureus
August 2024
Department of Orthopaedics and Traumatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Article Synopsis
- * This study involved 32 patients undergoing either total knee or hip replacement and aimed to evaluate two pain management approaches: epidural analgesia (Group A) vs. a multimodal drug cocktail (Group B).
- * Results showed that while preoperative pain scores were similar, Group B experienced lower pain levels post-surgery at various intervals, indicating the cocktail might be more effective for pain management during recovery.
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