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Surgical treatment of cerebellar pontine angle lipoma combined with trigeminal neuralgia: A case report.

Medicine (Baltimore)

January 2025

Department of Head and Neck Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Rationale: Cerebellar pontine angle lipomas with trigeminal neuralgia are rare. The treatment choice is influenced by whether the pain is caused by the lipoma or the compression of blood vessels. Herein, we aimed to report a case of the disease and provide a reference for its treatment.

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Background: Even a gross total resection of a benign epidermoid tumor (ET) carries a high risk of recurrence. The management strategy mostly involves redo surgical excision but at a significant cost of morbidity and mortality. The role of adjuvant radiation therapies in this scenario is still undefined.

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Article Synopsis
  • Ganglioneuroma is a rare benign tumor that can originate from the sympathetic nerves, and this case describes the second instance of such a tumor arising from the fifth cranial nerve in a pediatric patient.
  • A 7-year-old boy presented with left-sided facial symptoms and seizures, and imaging revealed a significant lesion near the fifth nerve, which was confirmed to be a ganglioneuroma through histopathological analysis.
  • Surgical removal of the tumor was performed successfully using a specific approach, highlighting the importance of considering ganglioneuroma in similar clinical scenarios involving lesions in the brain's Meckel's cave area.
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Trigeminal malignant peripheral nerve-sheath tumor: Systematic review, and case report treated by proton-beam therapy.

Neurochirurgie

December 2024

CHU de Caen Normandie, Department of Neurosurgery, Caen F-14000, France; INSERM, UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Caen, F-14000, France.

Background: Malignant peripheral nerve-sheath tumor (MPNST) is rare, occurring in approximately 0.001% of the general population. Cases involving cranial nerves, and particularly the trigeminal nerve (V), are exceptionally rare, with only 36 cases reported in a literature review in 2013.

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