Background: Research on older adults who sustain a traumatic brain injury (TBI) has predominantly been on civilian, nonveteran populations. Military populations experience higher rates of TBI and often experience the additive effects of TBI and other comorbid disorders, including posttraumatic stress disorder and/or substance use that may increase disability over time.
Objective: To investigate predictors of functional independence trajectories over the 5 years after TBI in veterans 55 years or older at injury.
Setting: Five Veterans Affairs (VA) polytrauma rehabilitation center (PRC) inpatient rehabilitation programs.
Participants: Veterans who experienced their TBI at 55 years or older and had completed one or more Functional Independence Measure (FIM) Motor and Cognitive measure at 1, 2, or 5 years after TBI (n = 184) from the VA TBI Model Systems national database.
Design: Retrospective analysis of observational data using hierarchical linear models.
Main Measures: FIM Motor and Cognitive scores at 1, 2, and 5 years after TBI.
Results: Motor and cognitive functioning decreased over time. Lower FIM Motor trajectories occurred in participants who had pre-TBI functional limitations in going out of the home and with longer posttraumatic amnesia (PTA). FIM Motor scores decreased over time, and the decrease was steeper for those with a moderate or severe injury. Lower FIM Cognitive trajectories occurred in participants who had problematic substance use at baseline and among those with longer PTA. FIM Cognitive scores decreased at a steeper rate for participants with greater injury severity.
Conclusions: Similar to previously published studies in civilian populations, older veterans with TBI may be at risk for functional and cognitive decline. This study's findings increase the field's understanding of functional trajectories after TBI in older adults and may help identifty those who are at risk for lower functional outcomes.
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http://dx.doi.org/10.1002/pmrj.13312 | DOI Listing |
PM R
January 2025
Department of Psychology, University of Virginia, Charlottesville, Virginia, USA.
Background: Research on older adults who sustain a traumatic brain injury (TBI) has predominantly been on civilian, nonveteran populations. Military populations experience higher rates of TBI and often experience the additive effects of TBI and other comorbid disorders, including posttraumatic stress disorder and/or substance use that may increase disability over time.
Objective: To investigate predictors of functional independence trajectories over the 5 years after TBI in veterans 55 years or older at injury.
Jpn J Compr Rehabil Sci
December 2024
Department of Rehabilitation Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Unlabelled: Yamaguchi A, Kanazawa Y, Hirano S, Aoyagi Y. A Case with Left Hemiplegia after Cerebral Infarction with Improved Walking Ability Through Robot-assisted Gait Training Combined with Neuromuscular Electrical Stimulation for Foot Drop. Jpn J Compr Rehabil Sci 2024; 15: 88-93.
View Article and Find Full Text PDFAnn Clin Transl Neurol
January 2025
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.
Objective: Patients with amyotrophic lateral sclerosis (ALS) caused by superoxide dismutase 1 (SOD1) gene mutations (SOD1 ALS) treated with tofersen have shown slowing of disease progression, and disease stabilization with recovery of function in some patients. We report our clinical experience with treating patients with SOD1 ALS and the effects of tofersen on outcome measures.
Methods: This was a single-center observational study of patients with SOD1 ALS receiving treatment with tofersen.
J Neuroeng Rehabil
January 2025
Division of Rehabilitation Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Background: Despite the reported efficacy of overground robotic exoskeleton (ORE) for rehabilitation of mobility post-stroke, its effectiveness in real-world practice is still debated. We analysed prospectively collected data from Improving Mobility Via Exoskeleton (IMOVE), a multicentre clinical implementation programme of ORE enrolling participants with various neurological conditions and were given options to choose between 12 sessions of ORE or conventional therapy (control).
Methods: This is analysis of participants under IMOVE who fulfilled the following criteria (i) primary diagnosis was stroke (ischemic, hemorrhagic; first or recurrent), (ii) onset of stroke was within 9 months and (iii) the intervention was during inpatient stay.
J Neurotrauma
January 2025
Department of Physical Medicine & Rehabilitation, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Traumatic brain injury (TBI) and subsequent post-traumatic epilepsy (PTE) often impair daily activities and mental health (MH), which contribute to long-term TBI-related disability. PTE also affects driving capacity, which impacts functional independence, community participation, and satisfaction with life (SWL). However, studies evaluating the collective impact of PTE on multidimensional outcomes are lacking.
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