Introduction: Marathon running has become increasingly popular among amateur athletes, many of whom maintain speeds of 8-9 km/h. However, existing methods for estimating oxygen consumption (VO) during running and walking-such as the American College of Sports Medicine (ACSM) equations and commercial activity monitors-often lack accuracy and transparency. This study introduces the Hata-Yanagiya Physical Activity Calculation (HYPAC) system, a novel approach for estimating VO using Global Positioning System (GPS) and map data.
Methods: The HYPAC system was developed through regression equations based on metabolic equivalents (METs) and slope data. To validate the system, 10 university students (5 runners, 5 non-runners) completed a 5 km course while equipped with a GPS device and a portable metabolic measurement system. VO estimates from the HYPAC system were compared with measured values and those calculated using ACSM equations.
Results: The HYPAC system demonstrated high accuracy in estimating VO, with a relative error of -0.03 [95% confidence intervals (CI): -0.14, 0.08] compared to measured values. For the running group, the HYPAC system achieved the lowest absolute mean relative error (0.02). In the mixed running/walking group, the HYPAC system maintained strong performance with a relative error of -0.07 (95% CI: -0.26, 0.12).
Discussion: The HYPAC system provides a transparent and accurate method for estimating VO during walking and running, outperforming existing methods under varied conditions. Its open-source framework encourages further validation and improvement by researchers and practitioners. Future studies should address limitations such as sample size and population diversity to enhance the system's applicability.
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http://dx.doi.org/10.3389/fspor.2024.1522214 | DOI Listing |
Front Sports Act Living
January 2025
Graduate School of Health and Sports Science, Juntendo University, Inzai, Japan.
Introduction: Marathon running has become increasingly popular among amateur athletes, many of whom maintain speeds of 8-9 km/h. However, existing methods for estimating oxygen consumption (VO) during running and walking-such as the American College of Sports Medicine (ACSM) equations and commercial activity monitors-often lack accuracy and transparency. This study introduces the Hata-Yanagiya Physical Activity Calculation (HYPAC) system, a novel approach for estimating VO using Global Positioning System (GPS) and map data.
View Article and Find Full Text PDFTalanta
December 2024
Department of Forensic Medicine, Huazhong University of Science and Technology, #13 Hangkong Road, Wuhan, 430030, China. Electronic address:
In this work, electromembrane extraction (EME) was used for the first time to separate aconitine (AC), mesaconitine (Mes-AC) and hypaconitine (Hyp-AC) from biological samples and Chinese herbal medicines. Efficient EME of polar and high molecular weight aconitine alkaloids from different sample matrices was achieved with the solvent of 1-ethyl-2-nitrobenzene (ENB). Under the optimal EME conditions, EME provided recoveries for all targets in the range of 72%-74 %, 85%-103 % and 92%-94 % for whole blood, urine and aqueous samples.
View Article and Find Full Text PDFEukaryot Cell
May 2012
Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Dermatophytes are the most common cause of superficial mycoses in humans and animals. They can coexist with their hosts for many years without causing significant symptoms but also cause highly inflammatory diseases. To identify mechanisms involved in the modulation of the host response during infection caused by the zoophilic dermatophyte Arthroderma benhamiae, cell wall-associated surface proteins were studied.
View Article and Find Full Text PDFPretreatment measures of hypothalamic-pituitary-adrenocortical (HYPAC) function in depressed, manic, and healthy normal subjects showed that nonsuppression on the dexamethasone suppression test (DST) had less positive predictive value for major diagnostic category and was more frequent in normals (8/77) than recently reported, although it was yet more frequent in depressed patients (35/111). Nonsuppression was common in manics (8/16), was similar in unipolar and bipolar depressed patients (35% and 27%, respectively), and did not segregate with melancholic, endogenous, or psychotic depression subtypes. Patterns of post-DST plasma cortisol concentration other than simple escape or nonescape from suppression were common.
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