Perception of without infection induces in .

pathogenic susceptibility is influenced by the worm's detection of its environment and its capacity to resist and resolve damage following infection. Here, we use a model where worms can sense, but not ingest, the pathogen (EF) We identify that perception of EF without infection induces the stress-response gene further identify that neural and intestinal signaling genes are necessary for induction without active infection. Finally, we show that overexpression is sufficient to extend lifespan with EF exposure, while KO is not detrimental, suggesting that additional expression benefits worms in this condition.