Background: The vital statistics in the third world countries are poor and have witnessed minimal improvement over the years with childhood mortality in Nigeria remaining one of the highest among the developing countries despite various child survival programmes. Child survival strategies can only be efficient if the major reasons for morbidity are known. The objective of this retrospective study was to review the patterns of childhood mortality at the emergency room of the Federal Teaching Hospital, Ido-Ekiti (FETHI).
Materials And Methods: This study was conducted at the Children Emergency room of FETHI. Admission, discharge records and the case notes of the patients who died from September 2017 to October 2022 at the emergency units were retrospectively reviewed to extract the data on the age, sex, diagnosis, and duration of stay on admission before demise. A p-value of <0.05 was accepted as statistically significant.
Results: There was a total of 2503 admissions with a M: F ratio of 1.25:1. The mortality rate was 3.9%. Age at demise was independent of the sex of the patients with a p-value of 0.33. More deaths occurred within six to 72 hours on admission and 68% of deaths in the EPU were U-5. Sepsis and malaria were the leading causes of death.
Conclusions: The high incidence of mortality among under-5 largely from preventable causes of death stresses the need to strengthen the existing childhood preventive measures.
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Nihon Koshu Eisei Zasshi
January 2025
Graduate School of Engineering Science, Osaka University.
Objectives Although childhood cancer treatment has recently become centralized at specialized hospitals worldwide, the relationship between mortality ratios and living in rural areas or traveling long distances for treatment remains controversial. In the present study, we examined whether regional differences in patient mobility and mortality ratios exist in Japan.Methods We investigated 10,713 patients with cancer aged ≤18 years, diagnosed between 2016 and 2019, registered in the national cancer registry data.
View Article and Find Full Text PDFWest Afr J Med
September 2024
Department of Paediatrics, Federal Teaching Hospital, Ido-Ekiti. Email: Tel: +2348035741951.
Background: The vital statistics in the third world countries are poor and have witnessed minimal improvement over the years with childhood mortality in Nigeria remaining one of the highest among the developing countries despite various child survival programmes. Child survival strategies can only be efficient if the major reasons for morbidity are known. The objective of this retrospective study was to review the patterns of childhood mortality at the emergency room of the Federal Teaching Hospital, Ido-Ekiti (FETHI).
View Article and Find Full Text PDFLife (Basel)
December 2024
Department of Translational Medical Sciences, Pediatric Section, Federico II University of Naples, 80131 Naples, Italy.
MyD88 deficiency is a rare inborn error of immunity (IEI) characterized by susceptibility to pyogenic infections without overt signs of inflammation. Half of the reported patients belong to Roma descent, an itinerant ethnic group living mostly in Europe, with an increased risk of childhood mortality due to limited access to healthcare services. We describe three unrelated patients from the Campania region in Italy with MyD88 deficiency, all belonging to Roma descent and displaying severe or recurrent infections in early infancy.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Experimental Oncology Laboratory, National Institute of Pediatrics, Mexico City 04530, Mexico.
Acute lymphoblastic leukemia (ALL) is a malignant neoplasm with the highest incidence in the pediatric population. Although the 5-year overall survival is greater than 85%, in emerging countries such as Mexico, the mortality rate is high. In Mexico, B-ALL is the most common type of childhood cancer; different characteristics suggest the presence of the disease; however, the prognosis is dependent on clinical and laboratory features, and no adverse prognostic molecular marker for B-ALL has yet been identified.
View Article and Find Full Text PDFChildren (Basel)
January 2025
Centro de Investigación Biomédica de La Rioja (CIBIR), 26006 Logroño, Spain.
Background: Childhood obesity is a major public health concern, being linked to an increased risk of metabolic disorders and cardiovascular disease. Even in childhood, obesity is associated with systemic low-grade inflammation, which is a critical factor in the development of atherosclerosis and a predictor of cardiovascular morbidity and mortality.
Objectives: To describe the prevalence of obesity and examine the relationship between IL-6, TNF-α, adiponectin, leptin, the leptin/adiponectin (L/A) ratio, and Klotho levels with BMI in children.
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