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Treatment of pediatric drug-resistant generalized epilepsy with responsive neurostimulation of the centromedian nucleus of the thalamus: A case series of seven patients.
Epilepsy Res
January 2025
Division of Pediatric Neurology, Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 8th Floor Faculty Pavilion, 4401 Penn Ave., Pittsburgh, PA 15224, United States. Electronic address:
Purpose: Responsive neurostimulation of the centromedian nucleus of the thalamus (CM RNS) is being investigated for treatment of drug-resistant generalized epilepsy with promising results. The aim of this study is to report outcomes of seven patients with pediatric-onset drug-resistant generalized epilepsy, including both genetic generalized epilepsy (GGE) and Lennox-Gastaut syndrome (LGS), who underwent treatment with bilateral CM RNS.
Methods: A retrospective chart review was performed for patients with drug-resistant generalized epilepsy who underwent treatment with bilateral CM RNS at Children's Hospital of Pittsburgh from 2020 to 2022.
Identification of an ANCA-associated vasculitis cohort using deep learning and electronic health records.
Int J Med Inform
January 2025
Rheumatology and Allergy Clinical Epidemiology Research Center and Division of Rheumatology, Allergy, and Immunology, and Mongan Institute, Department of Medicine, Massachusetts General Hospital Boston MA USA. Electronic address:
Background: ANCA-associated vasculitis (AAV) is a rare but serious disease. Traditional case-identification methods using claims data can be time-intensive and may miss important subgroups. We hypothesized that a deep learning model analyzing electronic health records (EHR) can more accurately identify AAV cases.
View Article and Find Full Text PDFEvaluation of an interprofessional education workshop about common ocular conditions for pharmacy and optometry students.
Clin Exp Optom
January 2025
Division of Pharmacy and Optometry, University of Manchester, Manchester, UK.
Clinical Relevance: Interprofessional education and collaborative working are known to improve patient outcomes. The evidence to support this approach in optometry is lacking.
Background: There is no published evidence into the effectiveness of interprofessional education for pharmacy and optometry students.
Accuracy of ChatGPT 3.5, 4.0, 4o and Gemini in diagnosing oral potentially malignant lesions based on clinical case reports and image recognition.
Med Oral Patol Oral Cir Bucal
January 2025
15, Trauma Centre, District Hospital Neemuch Madhya Pradesh - 458441, India
Background: The accurate and timely diagnosis of oral potentially malignant lesions (OPMLs) is crucial for effective management and prevention of oral cancer. Recent advancements in artificial intelligence technologies indicates its potential to assist in clinical decision-making. Hence, this study was carried out with the aim to evaluate and compare the diagnostic accuracy of ChatGPT 3.
View Article and Find Full Text PDFTeaching oral and maxillofacial pathology and oral medicine in undergraduate and postgraduate in Latin America.
Med Oral Patol Oral Cir Bucal
January 2025
Health Science Postgraduate Program State University of Montes Claros Campus Universitário Prof. Darcy Ribeiro Av. Prof. Rui Braga, s/n Vila Mauriceia, Postal Code 39401-089 Montes Claros - MG, Brazil
Background: Oral and Maxillofacial Pathology (OP) and Oral Medicine (OM) are specialties in dentistry responsible for diagnosis and management of diseases affecting the oral and maxillofacial regions, and to best of our knowledge no information about teaching of OP and OM in undergraduate and postgraduate courses in Latin America have been described. The aim of the present study was to evaluate dimensions related to the teaching of OP and OM in South America and Mexico.
Material And Methods: A structured questionnaire was elaborated and sent to 10 countries, with a professional in each country responsible for answering it.
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