Unlabelled: Ultrasound imaging plays an important role in the early detection and management of breast cancer. This study aimed to evaluate the imaging performance of a range of clinically-used breast ultrasound systems using a set of novel spherical lesion contrast-detail (C-D) and anechoic-target (A-T) phantoms.

Methods: C-D and A-T phantoms were imaged using a range of clinical breast ultrasound systems and imaging modes. A novel sensitive imaging performance metric, the Detectability Score (DS), was proposed which encompasses the Lesion Contrast to Noise Ratio (L) weighted by the lesion depth and diameter. A geometry-based theoretical model comparing L measured using spherical and cylindrical phantom anechoic/lesion targets was developed to investigate the influence of slice thickness on focal lesion detectability.

Results: L and DS metrics derived from phantom image measurments were capable of differentiating the imaging performance of a range of ultrasound systems and advanced imaging modes, with the -2 dB contrast lesion targets offered as the most challenging to resolve. The geometry-based theoretical model, validated against phantom measurements, demonstrated the significant influence of slice thickness on focal lesion detectability, highlighting the need for increased availability of low contrast resolution spherical target phantoms for clinically realistic performance evaluation.

Conclusions: The performance metrics coupled with the -1 dB contrast targets provide scope for evaluating future technological improvements in ultrasound systems. Given the high dependence of breast cancer care on high quality ultrasound imaging techniques, there is a need for evaluating imaging performance using clinically relevant test objects.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmp.2025.104910DOI Listing

Publication Analysis

Top Keywords

imaging performance
16
ultrasound systems
16
breast ultrasound
12
ultrasound imaging
12
imaging
9
contrast-detail c-d
8
c-d anechoic-target
8
anechoic-target a-t
8
a-t phantoms
8
breast cancer
8

Similar Publications

Background: Owing to the risk for septic arthritis, traumatic arthrotomies are an urgent surgical problem for the treating orthopaedic surgeon. Traditionally, diagnosis is with the saline load test (SLT), although in the awake patient is an invasive and potentially painful procedure. While computerized tomography (CT) has been shown to be a reliable diagnostic tool for traumatic arthrotomies of other joints, its role has only recently been investigated in the setting of ankle arthrotomy.

View Article and Find Full Text PDF

Recent advances in small-joint arthroscopy and cutting-edge magnetic resonance imaging systems have enabled orthopedic surgeons to perform more complex repairs of the wrist. Such repairs can include those of the triangular fibrocartilage complex (TFCC) of the wrist that necessitates a reappraisal of its morphometry with special emphasis on the relationship between its articular disc (AD) and surrounding tissues. The TFCC AD is a fibrocartilaginous, biconcave structure located between the ulnar styloid process and the carpal bones of the wrist.

View Article and Find Full Text PDF

Background And Aims: The performance of non-invasive liver tests (NITs) is known to vary across settings and subgroups. We systematically evaluated whether the performance of three NITs in detecting advanced fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) varies with age, sex, body mass index (BMI), type 2 diabetes mellitus (T2DM) status or liver enzymes.

Methods: Data from 586 adult LITMUS Metacohort participants with histologically characterised MASLD were included.

View Article and Find Full Text PDF

Background: Degeneration of the basal forebrain cholinergic system is a hallmark feature shared by Alzheimer's disease (AD) and Lewy body disease (LBD) whereas hippocampus atrophy is more specifically related to AD. We aimed to investigate the relationship between basal forebrain and hippocampus atrophy, cognitive decline, and neuropathology in a large autopsy sample.

Methods: Data were obtained from the National Alzheimer's Coordinating Center (NACC).

View Article and Find Full Text PDF

Purpose: Wearable electronic low vision enhancement systems (wEVES) improve visual function but are not widely adopted by people with vision impairment. Here, qualitative research methods were used to investigate the usefulness of wEVES for people with age-related macular degeneration (AMD) after an extended home trial.

Methods: Following a 12-week non-masked randomised crossover trial, semi-structured interviews were completed with 34 participants with AMD, 64.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!