The phytochemical profile of various plant species reveals that some compounds possess notable antioxidant and antimicrobial properties. In this study we investigated for the first time, the antioxidant activity (FRAP, DPPH and TAC), total phenolic contents and total flavonoid contents of Delile ex Godr flowers extracts (-hexane, ethyl acetate and methanol) as well as their antimicrobial activity. The results obtained showed that the methanol extract contained the highest content of total phenolics (346.7 mg GAE/g DE) and flavonoids (339.9 mg QE/g) as it exhibited the strongest antioxidant activity. Furthermore flower extracts have been tested for their activity against gram-positive and gram-negative bacteria and an interesting activity was obtained with methanol extract (MICs = 31.25 µg.mL). The chemical composition of methanol extract was investigated using a high-performance liquid chromatographic method coupled with electrospray ionisation mass spectrometry (HPLC-ESI-MS). Therefore, 28 compounds were detected among them 18 were identified as flavonoids, phenolic acids and fatty acids.
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http://dx.doi.org/10.1080/14786419.2025.2457119 | DOI Listing |
Talanta
January 2025
Center for Multiplatform Metabolomics Studies (CEMM) at the Institute of Chemistry, University of Sao Paulo, Sao Paulo, SP, 05508-000, Brazil. Electronic address:
There is no consensus in the literature regarding the ideal protocol for obtaining and preparing cell samples for untargeted metabolomics. Nevertheless, the procedures must be carefully evaluated for proper and reliable results for each organism under study. This work proposes a novel protocol for determining intracellular metabolites in Leishmania promastigotes and is fully optimized for application in conjunction with gas chromatography-mass spectrometry platforms.
View Article and Find Full Text PDFNat Prod Res
January 2025
Department of Bioengineering and Biotechnology, Birla Institute of Technology, Ranchi, Jharkhand, India.
Current study investigates the medicinal applications of (Palash), the state flower of Jharkhand, India, focusing on synthesising biomodified copper oxide nanoparticles (CuO-NPs) and its antifungal properties. Flavonoid content in the flower extract was quantified by aluminium chloride colorimetric analysis. CuO-NPs were synthesised via co-precipitation method and then modified with methanolic flower extract.
View Article and Find Full Text PDFNat Prod Res
January 2025
College of Pharmacy, Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine, Guangxi University of Chinese Medicine, Nanning, China.
(L.) Jacq. has anti-inflammatory, analgesic, haemostatic and antioxidant effects, but its pharmacological components are still unclear.
View Article and Find Full Text PDFNat Prod Res
January 2025
Laboratory of Organic Chemistry LR17-ES08 (Natural Substances Team), Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
The phytochemical profile of various plant species reveals that some compounds possess notable antioxidant and antimicrobial properties. In this study we investigated for the first time, the antioxidant activity (FRAP, DPPH and TAC), total phenolic contents and total flavonoid contents of Delile ex Godr flowers extracts (-hexane, ethyl acetate and methanol) as well as their antimicrobial activity. The results obtained showed that the methanol extract contained the highest content of total phenolics (346.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
This study explores the development of electrospun nanofibers incorporating bioactive compounds from (Ashwagandha) root extract, focusing on optimizing extraction conditions and nanofiber composition to maximize biological activity and application potential. Using the Design of Experiment (DoE) approach, optimal extraction parameters were identified as 80% methanol, 70 °C, and 60 min, yielding high levels of phenolic compounds and antioxidant activity. Methanol concentration emerged as the critical factor influencing phytochemical properties.
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