In light of the demographic shift towards an aging population, there is an increasing prevalence of dementia among the elderly. The negative impact on mental health is preventing individuals from taking proper care of themselves. For individuals requiring hospital care, those receiving home care, or as a precaution for a specific individual, it is advantageous to utilize monitoring equipment to track their biological parameters on an ongoing basis. This equipment can minimize the risk of serious accidents or severe health hazards. The objective of the present research project is to design an armband with an accurate location tracking system. This is of particular importance for individuals with dementia and Alzheimer's disease, who frequently leave their homes and are unable to find their way back. The proposed armband also includes a fingerprint identification system that allows only authorized personnel to use it. Furthermore, in hospitals and healthcare facilities the biometric identification system can be used to trace periodic medical or nursing visits. This process improves the reliability and transparency of healthcare. The test results indicate that the armband functions in accordance with the desired design specifications, with performance evaluation of the main features including fall detection, where a hit rate of 100% was obtained, a fingerprint recognition test demonstrating accuracy from 88% to 100% on high-quality samples, and a GPS tracking test determining position with a difference of between 1.8 and 2.1 m. The proposed solution may be of benefit to healthcare professionals, supported housing providers, elderly people as target users, or their family members.
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http://dx.doi.org/10.3390/s25020455 | DOI Listing |
BMC Med Genomics
January 2025
Department of Surgery, Faculty of General of Medicine, Koya University, Koya, Kurdistan Region - F.R., KOY45, Iraq.
Background: During mammalian spermatogenesis, the cytoskeleton system plays a significant role in morphological changes. Male infertility such as non-obstructive azoospermia (NOA) might be explained by studies of the cytoskeletal system during spermatogenesis.
Methods: The cytoskeleton, scaffold, and actin-binding genes were analyzed by microarray and bioinformatics (771 spermatogenic cellsgenes and 774 Sertoli cell genes).
Sci Rep
January 2025
School of Mechanics and Engineering, Liaoning Technical University, Fuxin, 123000, China.
Uniaxial compression experiments were conducted on coal rock utilizing a computed tomography (CT) scanning system for real-time monitoring to explain the issue of gas volume significantly exceeding reservoir capacity during coal and gas outbursts. A percolation factor a which can make a significant contribution to the research on premonitory information of gas outbursts is introduced to determine whether percolation occurs in coal rock, and supports the outburst percolation theory. It was found that percolation probability and correlation length increase with greater porosity, and that the number of pore clusters decreases as porosity increases.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Hematology and Oncology, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Children's Hospital of Chongqing Medical University, No 136 Zhongshan 2 road, YuZhong district, Chongqing, 400014, China.
Genetic alterations play a pivotal role in leukemic clonal transformation, significantly influencing disease pathogenesis and clinical outcomes. Here, we report a novel fusion gene and investigate its pathogenic role in acute lymphoblastic leukemia (ALL). We engineer a transposon transfection system expressing the TOP2B::AFF2 transcript and introduce it into Ba/F3 cells.
View Article and Find Full Text PDFSci Data
January 2025
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
As the occurrence of human diseases and conditions increase, questions continue to arise about their linkages to chemical exposure, especially for per-and polyfluoroalkyl substances (PFAS). Currently, many chemicals of concern have limited experimental information available for their use in analytical assessments. Here, we aim to increase this knowledge by providing the scientific community with multidimensional characteristics for 175 PFAS and their resulting 281 ion types.
View Article and Find Full Text PDFNat Commun
January 2025
College of Chemistry, Nankai University, Tianjin, China.
Pathogenic intracellular bacteria pose a significant threat to global public health due to the barriers presented by host cells hindering the timely detection of hidden bacteria and the effective delivery of therapeutic agents. To address these challenges, we propose a tandem diagnosis-guided treatment paradigm. A supramolecular sensor array is developed for simple, rapid, accurate, and high-throughput identification of intracellular bacteria.
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