Genomic applications in beef cattle disease prevention have gained traction in recent years, offering new strategies for improving herd health and reducing economic losses in the livestock industry. Advances in genomics, including identification of genetic markers linked to disease resistance, provide powerful tools for early detection, selection, and management of cattle resistant to infectious diseases. By incorporating genomic technologies such as whole-genome sequencing, genotyping, and transcriptomics, researchers can identify specific genetic variants associated with resistance to pathogens like bovine respiratory disease and Johne's disease. These genomic insights allow for more accurate breeding programs aimed at enhancing disease resistance and overall herd resilience. Genomic selection, in particular, enables identification of individuals with superior genetic traits for immune function, reducing the need for antibiotic treatments and improving animal welfare. Moreover, precision medicine, powered by genomic data, supports development of tailored health management strategies, including targeted vaccination plans and antimicrobial stewardship. Incorporation of genomic tools in beef cattle management also offers the potential for early disease detection, facilitating proactive interventions that reduce the spread of infections. Despite challenges like cost, data interpretation and integration into current management systems, the potential advantages of genomic applications in disease prevention are substantial. As these technologies advance, they are anticipated to have crucial roles in improving sustainability (by enhancing herd performance), profitability (by improving overall herd longevity), and biosecurity (by decreasing the likelihood of disease outbreaks) of beef cattle production systems worldwide.
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http://dx.doi.org/10.3390/ani15020277 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759163 | PMC |
Animal
December 2024
Department of Crop Sciences, Grassland Science, Georg-August-University Göttingen, Von-Siebold-Strasse 8, 37075 Göttingen, Germany; Centre for Biodiversity and Sustainable Land Use, Büsgenweg 1, 37075 Göttingen, Germany.
Animal welfare is integral to sustainable livestock production, and pasture access for cattle is known to enhance welfare. Despite positive welfare impacts, high labour requirements hinder the adoption of sustainable grazing practices such as rotational stocking management. Virtual fencing (VF) is an innovative technology for simplified, less laborious grazing management and remote animal monitoring, potentially facilitating the expansion of sustainable livestock production.
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December 2024
Alta Genetics Brasil Ltda., Uberaba 38055-010, Brazil.
Timed artificial insemination (TAI) is a technology widely used in cattle production based on controlling ovarian follicular growth. This study analyzed a large database aiming to determine the influence of several intrinsic and extrinsic female factors, as well as their interactions to determine risk factors and produce prediction ability in beef cattle. A total of 1 832 999 TAIs conducted on 2 002 farms across South American countries were considered for the analysis, including 15 main fixed effects or interactions in the statistical model, in addition to five random effects.
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January 2025
Key Laboratory of Livestock and Poultry Multi-Omics of MARA, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
This study was developed with the goal of exploring the impact of capsaicin on ruminal fermentation and ruminal bacteria in beef cattle affected by high-grain diet-induced subacute ruminal acidosis (SARA). In total, 18 healthy Simmental crossbred cattle were randomized into three separate groups ( = 6/group): (1) control diet (CON; forage-to-concentrate ratio = 80:20); (2) high-grain diet (SARA; forage-to-concentrate ratio = 20:80); and (3) high-grain diet supplemented with capsaicin (CAP; 250 mg/cattle/day). The study was conducted over a 60-day period.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6610, USA.
Genomic applications in beef cattle disease prevention have gained traction in recent years, offering new strategies for improving herd health and reducing economic losses in the livestock industry. Advances in genomics, including identification of genetic markers linked to disease resistance, provide powerful tools for early detection, selection, and management of cattle resistant to infectious diseases. By incorporating genomic technologies such as whole-genome sequencing, genotyping, and transcriptomics, researchers can identify specific genetic variants associated with resistance to pathogens like bovine respiratory disease and Johne's disease.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
To investigate the impact of maternal microbiota during lactation in different beef cattle breeds on their own immune levels, milk quality, and the growth and development of their offspring, this study measured the immune parameters, intestinal microbiota diversity, and milk quality of Pingliang red cattle and Simmental cattle, and performed a correlation analysis with the growth and development of their offspring. Our study showed that during lactation, Pingliang red cattle had significantly higher IL-6 levels than Simmental cattle, while the latter exhibited higher levels of immune factors such as IgG, IgA, IgM, IL-1β, and TNFα. The analysis of the intestinal microbiota of lactating cows found that Pingliang red cattle were rich in and , while Simmental cattle had a higher proportion of Actinobacteria.
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