Background: Understanding fetal growth is essential for predicting perinatal outcomes and long-term health implications. This study explores the correlation between ultrasound parameters and gestational age in the Minangkabau ethnic group, focusing on the biometric variables biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), and humerus length (HL) during the second trimester.
Methods: Conducted from December 2020 to December 2021, the research employed a cross-sectional design at the Fetomaternal clinic of Hospital M. Djamil Padang and affiliated hospitals. Pregnant women (n = 600) meeting inclusion criteria were sampled consecutively. Univariate, bivariate (Pearson correlation test), and multivariate (linear regression) analyses were performed using SPSS software.
Results: Demographically, most participants were 21-30 years old, primigravida, with senior high school education, and employed. Fetal biometric measurements displayed increasing variability with gestational age. AC exhibited the strongest correlation (r = 0.95, p < 0.005) with gestational age during the second trimester. The study validated the accuracy of AC in estimating gestational age based on LMP (r = 0.95, p = 0.0001).
Conclusion: This study contributes to the understanding of fetal growth dynamics, emphasizing the reliability of ultrasound parameters in estimating gestational age during the second trimester, particularly in the Minangkabau ethnic group. The strong correlation, especially with AC, enhances the precision of due date predictions and refines prenatal care strategies. However, limitations include the study's focus on a single ethnic group, potentially restricting generalizability. Future research should explore fetal growth dynamics across diverse populations, incorporate longitudinal designs to assess growth trajectories, and evaluate additional maternal and environmental factors. Enhanced standardization of AC measurement techniques is also necessary to reduce variability and improve clinical utility.
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http://dx.doi.org/10.1186/s12884-024-07042-5 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759424 | PMC |
Pediatr Surg Int
January 2025
Division of Pediatric Surgery, Department of Surgery, University of Florida College of Medicine, PO Box 100119, Gainesville, FL, 32610-0119, USA.
Purpose: Initial recommendations for ECMO had relative contraindications for low birth weight (BW) or low gestational age (GA) babies. However, more recent literature has demonstrated improved and acceptable outcomes of ECMO in smaller neonates. The purpose of this study was to understand both utilization and survival in patients with lower GA and BW.
View Article and Find Full Text PDFCytotherapy
January 2025
Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. Electronic address:
Background/aims: Human mesenchymal stromal cells (hMSC) are multipotent adult cells commonly used in regenerative medicine as advanced therapy medicinal products. The expansion of these cells in xeno-free supplements is highly encouraged by regulatory agencies due to safety concerns. However, the number of supplements with robust performance and consistency for hMSC expansion are limited.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
This study investigated the correlation between quantitative echocardiographic characteristics within 3 days of birth and necrotizing enterocolitis (NEC) and its severity in preterm infants. A retrospective study was conducted on 168 preterm infants with a gestational age of < 34 weeks. Patients were categorized into NEC and non-NEC groups.
View Article and Find Full Text PDFSci Data
January 2025
School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China.
Ultrasound is a primary diagnostic tool commonly used to evaluate internal body structures, including organs, blood vessels, the musculoskeletal system, and fetal development. Due to challenges such as operator dependence, noise, limited field of view, difficulty in imaging through bone and air, and variability across different systems, diagnosing abnormalities in ultrasound images is particularly challenging for less experienced clinicians. The development of artificial intelligence (AI) technology could assist in the diagnosis of ultrasound images.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Public Health, Policy and Systems, University of Liverpool, Liverpool, UK.
Objectives: How are socioeconomic inequalities modified by, or how do they interact with, preterm birth?
Design: Narrative systematic review of quantitative observational studies of an interaction, or effect modification, between preterm birth and socioeconomic status.
Data Sources: Five databases were searched for studies published between January 2000 and June 2020. Title and abstract were reviewed to identify articles for dual screening.
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