Complex motor skills involve intricate sequences of movements that require precise temporal coordination across multiple body parts, posing challenges to mastery based on perceived error or reward. One approach that has been widely used is to decompose such skills into simpler, constituent movement elements during the learning process, thereby aligning the task complexity with the learners' capacity for accurate execution. Despite common belief and prevalent adoption, the effectiveness of this method remains elusive. Here we addressed this issue by decomposing a sequence of precisely timed coordination of movements across multiple fingers into individual constituent elements separately during piano practice. The results demonstrated that the decomposition training enhanced the accuracy of the original motor skill, a benefit not achieved through mere repetition of movements alone, specifically when skilled pianists received explicit visual feedback on timing error in the order of milliseconds during training. During the training, the patterns of multi-finger movements changed significantly, suggesting exploration of movements to refine the skill. By contrast, neither unskilled pianists who underwent the same training nor skilled pianists who performed the decomposition training without receiving visual feedback on the error showed improved skill through training. These findings offer novel evidences suggesting that decomposing a complex motor skill, coupled with receiving feedback on subtle movement error during training, further enhances motor expertise of skilled individuals by facilitating exploratory refinement of movements.
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http://dx.doi.org/10.1038/s42003-025-07562-6 | DOI Listing |
Neuroimage
January 2025
Movement & Neuroscience, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
When engaged in dynamic or continuous movements, action initiation involves modifying an ongoing motor program rather than initiating it from rest. Event-related theta synchronization over sensorimotor areas is a neurophysiological marker for modifying motor programs. We used electroencephalography (EEG) to examine how task complexity and age affect event-related synchronization (ERS) in the theta band during a dynamic bimanual, visuomotor pinch force task.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
January 2025
HUN-REN-SZTE Neuroscience Research Group, Hungarian Research Network, University of Szeged (HUN-REN-SZTE), Danube Neuroscience Research Laboratory, H-6725 Szeged, Hungary.
Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT) metabolism. Over 90% of the 5-HT precursor tryptophan (Trp) is metabolized via the Trp-kynurenine (KYN) metabolic pathway, which generates a variety of bioactive molecules. Dysregulation of KYN metabolism, particularly low levels of kynurenic acid (KYNA), appears to be linked to neuropsychiatric disorders.
View Article and Find Full Text PDFJ Integr Neurosci
January 2025
Department of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.
The complicated neurological syndrome known as multiple sclerosis (MS) is typified by demyelination, inflammation, and neurodegeneration in the central nervous system (CNS). Managing this crippling illness requires an understanding of the complex interactions between neurophysiological systems, diagnostic techniques, and therapeutic methods. A complex series of processes, including immunological dysregulation, inflammation, and neurodegeneration, are involved in the pathogenesis of MS.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, Madinah 41477, Saudi Arabia.
Background: Traumatic brain injury (TBI) is a leading cause of mortality worldwide and often results in substantial cognitive, motor, and psychological impairments, triggering oxidative stress, neuroinflammation, and neurodegeneration. This study examined the neuroprotective effects of azithromycin (AZI) in TBI.
Methods: TBI was induced in rats using the weight-drop method.
Sensors (Basel)
January 2025
School of Mechanical and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Silicon carbide (SiC) metal oxide semiconductor field-effect transistors (MOSFETs) are a future trend in traction inverters in electric vehicles (EVs), and their thermal safety is crucial. Temperature-sensitive electrical parameters' (TSEPs) indirect detection normally requires additional circuits, which can interfere with the system and increase costs, thereby limiting applications. Therefore, there is still a lack of cost-effective and sensorless thermal monitoring techniques.
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