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We have studied the presence and frequency of micronuclei in exfoliated oral mucosa cells of full-term newborns and their association with maternal prenatal factors. We report an analytical, observational, cross-sectional, prospective study that includes 97 preterm infants (<37 weeks), 37 newborns from mothers with comorbidities, and 60 newborns from mothers without comorbidities, in a tertiary public hospital. Oral mucosa cells were collected within 24 h after birth. The frequency of cells with micronuclei and karyolytic cells was significantly higher in the group whose mothers had some form of comorbidity. Mothers with comorbidities had a shorter gestational age; the number of cells with micronuclei was higher in mothers with preterm premature rupture of membranes; and there were fewer karyolytic cells.
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| http://dx.doi.org/10.1016/j.mrgentox.2024.503840 | DOI Listing |
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