During orthodontic treatment patients' oral condition changes, thus influencing the overall health. Therefore, the treatment approaches require regular revision and updates to new guidelines. This literature review aims to analyse the oral health status in orthodontic patients focusing on the importance and urgency of treatment, preventive approaches to complications, and effects of the appliances on the oral biome. The review used Google Scholar, PubMed, and Science Direct databases for article searches dating from 2000 to 2024 on the status of the oral cavity changes during orthodontic treatment. Results have shown that changes in the oral cavity do not depend on the type of orthodontic appliances, both qualitative and quantitative changes in the bacterial flora were detected in cases of using all types of appliances. Orthodontic appliances and treatment may deteriorate overall oral hygiene in patients, particularly when patients practice poor oral hygiene habits, increasing the risks of developing dental decays and periodontal diseases.
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Br J Hosp Med (Lond)
January 2025
Department of Urology, The Second Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.
Overactive bladder (OAB) is a prevalent chronic condition affecting approximately 12% of adults, with incidence increasing with age. While pharmacological and behavioural therapies are standard treatments, their efficacy is often limited by side effects and poor adherence. This study aimed to compare the therapeutic effects of precision magnetic stimulation guided by motor-evoked potential with general magnetic therapy in patients with OAB.
View Article and Find Full Text PDFBiomolecules
December 2024
Unit of Medical and Dental Sciences, Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Prion diseases, including Creutzfeldt-Jakob disease (CJD), are deadly neurodegenerative disorders characterized by the buildup of abnormal prion proteins in the brain. This accumulation disrupts neuronal functions, leading to the rapid onset of psychiatric symptoms, ataxia, and cognitive decline. The urgency of timely diagnosis for effective treatment necessitates the identification of strongly correlated biomarkers in bodily fluids, which makes our research crucial.
View Article and Find Full Text PDFCancers (Basel)
January 2025
Department of Cancer Biology, Cardinal Bernardin Cancer Center, Stritch School of Medicine Health Sciences Division, Loyola University Chicago, 2160 South First Avenue Building 112, Room 205, Maywood, IL 60153, USA.
Background/objectives: Prostate cancer (PCa) is the second leading cause of cancer-related death in men. The increase in incidence rates of more advanced and aggressive forms of the disease year-to-year fuels urgency to find new therapeutic interventions and bolster already established ones. PCa is a uniquely targetable disease in that it is fueled by male hormones (androgens) that drive tumorigenesis via the androgen receptor or AR.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Department of Pediatric Emergency, Regina Margherita Children's Hospital, A.O.U. Città della Salute e della Scienza di Torino, 10126 Turin, TO, Italy.
: To face antimicrobial resistance, antimicrobial stewardship programs (ASPs) have been implemented in the pediatric age, but the area of urgency remains understudied. We aimed to assess the impact of an educational program on optimizing antibiotic appropriateness in a pediatric ED. : We conducted a pre-post observational study with an audit, intervention, and feedback given to prescribers.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 97002, Taiwan.
The current study aimed to investigate the clinical comorbidities and urodynamic characteristics of a large cohort of women with dysfunctional voiding (DV) validated on a videourodynamic study (VUDS). Women who presented with VUDS-confirmed DV from 1998 to 2022 were retrospectively analyzed. Data on clinical symptoms, VUDS findings, and medical comorbidities including medical illness and previous surgical history were recorded and examined.
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